LONDON, Sept. 16, 2014 /PRNewswire/ -- This report analyzes the worldwide markets for Brachytherapy in US$ Thousands. The report provides separate comprehensive analytics for the US, Canada, Japan Europe, Asia-Pacific, Middle East, and Latin America. Annual estimates and forecasts are provided for the period 2013 through 2020. Also, a seven-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 36 companies including many key and niche players such as -
Best Medical International, Inc.
Boston Scientific Corporation
COOK Medical, Inc.
C. R. Bard, Inc.
Gammex, Inc.
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I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-2
Quantitative Techniques & Analytics I-3
Product Definition and Scope of Study I-3
II. EXECUTIVE SUMMARY
1. MARKET OVERVIEW II-1
Brachytherapy - A Prelude II-1
The US Leads the Brachytherapy Devices Market Developing
Regions to Spearhead Growth II-2
Brachytherapy Provides More Hope for Cancer Patients Compared
to EBRT II-2
Comparison of Brachytherapy Over EBRT in Prostate Cancer
Treatment II-3
Growing Cancer Cases in Developing Countries Bodes Well for
the Brachytherapy Market II-3
Recent Technological Advancements Show Promising Future for
the Brachytherapy Market II-4
2. MAJOR MARKET DRIVERS, TRENDS & ISSUES II-5
Increase in Diagnosed Cases of Cancer - A Major Growth Driver II-5
Table 1: World Cancer Incidence by Geographic Region and
Gender (2012): Number of New Cancer Cases Reported (in
Thousands) for Asia-Oceania, Europe, North America, Latin
America & The Caribbean, and Africa (includes corresponding
Graph/Chart) II-5
Table 2: New Cancer Cases in the World by Affected Site
(2012) (in Thousands) (includes corresponding Graph/Chart) II-6
Table 3: Cancer Incidence in Developed Nations By Site: 2012
(includes corresponding Graph/Chart) II-7
Table 4: Global Incidence of Common Cancers in Men (2012):
Number of New Cases Reported in Thousands for Lung &
Bronchus, Prostate, Colorectal, and Liver Cancers (includes
corresponding Graph/Chart) II-8
Table 5: Global Incidence of Common Cancers in Women (2012):
Number of New Cases Reported in Thousands for Breast,
Colorectal, Lung & Bronchus, and Liver Cancers (includes
corresponding Graph/Chart) II-8
Table 6: World Cancer Mortality by Geographic Region and
Gender (2012): Number of Cancer-Related Deaths (in Thousands)
for Asia-Oceania, Europe, North America, Latin America & the
Caribbean, and Africa (includes corresponding Graph/Chart) II-9
Table 7: Global Cancer Mortality in Men for Select Cancers
(2012): Number of Deaths in Thousands for Lung & Bronchus,
Liver, Colorectal, and Prostate Cancers (includes
corresponding Graph/Chart) II-9
Table 8: Global Cancer Mortality in Women for Select Cancers
(2012): Number of Deaths in Thousands for Breast, Lung &
Bronchus, Colorectal, and Liver Cancers (includes
corresponding Graph/Chart) II-10
Cancer Prone Sites based on Age II-10
Ballooning Global Population Offers Significant Growth
Opportunities II-10
Table 9: Top 25 Countries Worldwide in Terms of Population:
2010 & 2013 II-11
Rising Healthcare Needs of Aging Global Population Drives
Brachytherapy II-11
Table 10: Life Expectancy Rates at Birth by Geographic
Region: 1990 & 2011 (includes corresponding Graph/Chart) II-12
Table 11: Global Population Statistics for the 65+ Age Group
(2012) (includes corresponding Graph/Chart) II-13
Table 12: Percentage of Population Aged 65 and Above in
Europe, US, and Japan (1960-2030) (includes corresponding
Graph/Chart) II-14
Table 13: Elderly Population (65+ Years) as a Percentage of
the Total Population: 2025 (includes corresponding
Graph/Chart) II-14
Prostate Brachytherapy Offers Bright Prospects II-14
Reimbursement Scenario - A Major Issue II-15
Competition Heats Up in the Brachytherapy Market II-15
Table 14: Global Brachytherapy Devices Market by Leading
Players (2012): Percentage Market Share Breakdown of Value
Sales for Nucletron, Oncura, CR Brad, Varian, Theragenics,
Eckert and Ziegler BEBIG, and Others (includes corresponding
Graph/Chart) II-15
Macular Degeneration - An Emerging Brachytherapy Application II-16
APBI Therapy Rise in Popularity II-16
Balloon Brachytherapy Gains Prominence II-16
Radiation Safety - An Important Issue in Brachytherapy Treatment II-17
3. RESEARCH & STUDY FINDINGS II-18
Brachytherapy - Highly Benefitting Young Prostate Cancer Patients II-18
Research Reveals Lower Rate of Breast Preservation in Older
Women undergoing Brachytherapy Treatment II-18
Possibility of Hematuria, Up to Several Years after
Brachytherapy Treatment Completion II-18
Researchers at Duke University Develops a Biodegradable
Brachytherapy Treatment II-19
Study Finds Increased Risk of Complications after Breast
Brachytherapy II-19
Another Study Reveals Increased Risk of Re-occurrence of
Breast Cancer Using Brachytherapy II-19
Brachytherapy Found to be Useful in Treating High-Risk
Prostate Cancer Cases as well II-19
Brachytherapy - The Effective One among the Three Prostate
Cancer Treatment II-20
Brachytherapy - Cost Effective for Prostate Cancer Treatment
Compared to IMRT II-20
4. PROSTATE CANCER - A MAJOR BRACHYTHERAPY INDICATION II-21
Prostate Cancer - A Deadly Disease II-21
Brachytherapy Revolutionizes Prostate Cancer Treatment II-21
Side Effects Do Exist II-21
Seed Migration - A Cause of Concern? II-22
History Behind the Development II-23
Prostate Brachytherapy Procedure II-23
Seed Brachytherapy Clinical Outcomes II-24
Types of Brachytherapy Procedures for Prostate Cancer Treatment II-24
Interstitial brachytherapy II-24
Combination Radiotherapy II-25
Whole Pelvic Radiation Therapy II-25
5. OTHER MAJOR BRACHYTHERAPY INDICATIONS II-26
Breast Cancer II-26
Breast Brachytherapy - An Introduction II-26
How is Breast Brachytherapy Performed? II-26
Breast Brachytherapy Techniques II-27
Brain Brachytherapy II-27
Brain Tumor II-27
Types of Brain Tumor II-28
Treatment Techniques II-28
Brain Brachytherapy II-28
Whole Brain Radiation Therapy II-28
Bronchial Carcinoma II-29
Bronchial Brachytherapy II-29
Procedure II-29
Head and Neck Brachytherapy II-30
Cervical Brachytherapy II-30
Esophageal Brachytherapy II-30
Brachytherapy for Eyelid Tumors II-31
Other Indications II-31
6. PRODUCT OVERVIEW II-32
What is Brachytherapy? II-32
Implantable Prostate Seeds Brachytherapy II-32
Post-Operative Brachytherapy II-32
Mechanism of Action II-32
Brachytherapy - Under the Microscope II-33
Brachytherapy Sources II-33
The Team II-34
A Historical Perspective II-34
Brachytherapy - A Classification II-34
Types as Per Seed Positioning II-34
Mold Brachytherapy II-34
Interstitial Brachytherapy II-34
Endovascular Brachytherapy II-35
Stent-Based Techniques II-35
Catheter-Based Techniques II-35
Intracavitary Brachytherapy II-36
Classification as per Irradiation Duration II-36
Temporary Brachytherapy II-36
Permanent Brachytherapy II-36
Categorization as per the Dose Rate II-37
HDR Brachytherapy II-37
LDR Brachytherapy II-37
PDR Brachytherapy II-38
PDR Brachytherapy Vs. HDR Brachytherapy II-38
PDR Brachytherapy Vs. LDR Brachytherapy II-38
7. BRACHYTHERAPY EQUIPMENT II-39
Brachytherapy Systems II-39
Remote Afterloading Machines II-39
Manual Afterloading Machines II-39
Brachytherapy Applicators II-40
Types of Brachytherapy Applicators II-40
Automated Brachytherapy Applicators II-40
Manual Brachytherapy Applicators II-40
8. RECENT INDUSTRY ACTIVITY II-41
IsoRay Obtains CE Mark Extension for Cesium-131 seeds Products
Range II-41
AMIC to Pursue Regulatory Down-Classification of Brachytherapy
Cancer Product II-41
Elekta Receives FDA Approval for Esteya® Electronic Brachytherapy II-41
Advanced Medical Isotope Corporation Submits 510(k) Pre-Market
Notification of Yttrium-90 RadioGel™ Brachytherapy II-41
Cianna Medical Obtains Approval for SAVI Breast Brachytherapy
in Japan II-41
Accelyon Enters into a Supply Agreement with AnazaoHealth
Corporation II-41
Civco Obtains FDA Approval for Ultrasound-guided Brachytherapy II-42
Nucletron Launches Esteya II-42
Nucletron, an Elekta company Receives CE marking for Esteya II-42
Theragenics Signs Agreement with Accelyon II-42
BTG Divests Brachytherapy Business to Eckert & Ziegler II-42
iCAD Receives FDA Clearance of Cervical Applicator for Xoft
Electronic Brachytherapy System II-42
iCAD Enters into Distribution Agreements of Xoft Axxent®
Electronic Brachytherapy System in Russia and Asia II-42
Theragenics Receives Patent for Expandable Brachytherapy Device II-42
Elysian Capital Acquires Accelyon Limited II-43
Eckert & Ziegler BEBIG Acquires MRNI II-43
Theragenics Enters into Agreement with Oncura II-43
Nucletron Receives Approval for Digital Brachytherapy
Afterloader in Japan II-43
Varian Medical Systems Rolls Out Latest Version of Vitesse™ II-43
9. FOCUS ON SELECT PLAYERS II-44
Best Medical International, Inc. (US) II-44
Best Vascular, Inc. (US) II-44
Boston Scientific Corporation (US) II-44
COOK Medical, Inc. (US) II-44
C. R. Bard, Inc. (US) II-45
Eckert & Ziegler Strahlen & Medizintechnik AG (Germany) II-45
Gammex, Inc. (US) II-46
Nucletron BV (Netherlands) II-46
Oncura, Inc. (US) II-47
Sirtex Medical Limited (Australia) II-47
Theragenics Corporation (US) II-47
Varian Medical Systems, Inc. (US) II-48
Xoft, Inc. (US) II-48
10. GLOBAL MARKET PERSPECTIVE II-49
Table 15: World Recent Past, Current & Future Analysis for
Brachytherapy Devices by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific, Middle East, and Latin America
Markets Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2013 through 2020 (includes
corresponding Graph/Chart) II-49
Table 16: World Historic Review for Brachytherapy Devices by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific,
Middle East, and Latin America Markets Independently Analyzed
with Annual Sales Figures in US$ Thousand for Years 2006
through 2012 (includes corresponding Graph/Chart) II-50
Table 17: World 15-Year Perspective for Brachytherapy Devices
by Geographical Region - Percentage Breakdown of Revenues for
US, Canada, Japan, Europe, Asia-Pacific, Middle East, and
Latin America Markets for Years 2006, 2014 and 2020 (includes
corresponding Graph/Chart) II-51
III. MARKET
1. THE UNITED STATES III-1
A.Market Analysis III-1
Cancer Presumes Epidemic Proportion III-1
Table 18: New Cancer Cases by Gender and Affected Site in
the US (2013) III-1
Growing Cancer Prevalence Drives Brachytherapy Demand III-3
Brachytherapy - Effective Option for Cancer Treatment III-3
Rapid Growth in Prostate Brachytherapy Market III-4
Technology Advancements Accelerate Growth III-4
Breast Brachytherapy Witnesses Slow Growth III-4
Brachytherapy Treatment for Cervical Cancer Declines,
Despite High Survival Rates III-4
Balloon Brachytherapy Makes Inroads into the Mainstream Market III-5
Reimbursement Scenario III-5
Growth Drivers III-6
Ongoing Research Activities Drive Acceptance of Brachytherapy III-6
Influx of New Players Drives Growth III-6
New Developments Propel Market Growth III-6
Strategic Corporate Developments III-7
Focus on Select Players III-8
B.Market Analytics III-12
Table 19: The US Recent Past, Current & Future Analysis for
Brachytherapy Devices Market Analyzed With Annual Sales
Figures in US$ Thousand for Years 2013 through 2020
(includes corresponding Graph/Chart) III-12
Table 20: The US Historic Review for Brachytherapy Devices
Market Analyzed With Annual Sales Figures in US$ Thousand
for Years 2006 through 2012 (includes corresponding
Graph/Chart) III-13
2. CANADA III-14
Market Analysis III-14
Table 21: Canadian Recent Past, Current & Future Analysis
for Brachytherapy Devices Market Analyzed With Annual Sales
Figures in US$ Thousand for Years 2013 through 2020
(includes corresponding Graph/Chart) III-14
Table 22: Canadian Historic Review for Brachytherapy Devices
Market Analyzed with Annual Sales Figures in US$ Thousand
for Years 2006 through 2012 (includes corresponding
Graph/Chart) III-15
3. JAPAN III-16
A.Market Analysis III-16
Strategic Corporate Developments III-16
B.Market Analytics III-17
Table 23: Japanese Recent Past, Current & Future Analysis
for Brachytherapy Devices Market Analyzed With Annual Sales
Figures in US$ Thousand for Years 2013 through 2020
(includes corresponding Graph/Chart) III-17
Table 24: Japanese Historic Review for Brachytherapy Devices
Market Analyzed with Annual Sales Figures in US$ Thousand
for Years 2006 through 2012 (includes corresponding
Graph/Chart) III-18
4. EUROPE III-19
A.Market Analysis III-19
Debt Crisis in Europe Affects Healthcare Industry III-19
European Healthcare System: In a State of Transition? III-19
Cancer Trends III-19
Table 25: Cancer Incidence in Europe by Site: 2012 (in
Thousands) (includes corresponding Graph/Chart) III-20
Brachytherapy in Europe III-21
Aging Population to Drive Demand for Brachytherapy III-21
Table 26: Population Breakup by Age Group for Select
European Countries: 2012 (As a % of Total Population)
(includes corresponding Graph/Chart) III-22
New EU Law to Drive Demand for Brachytherapy Devices III-22
Prostate Brachytherapy Gains Strength III-23
Competitive Analysis III-23
Strategic Corporate Developments III-23
B.Market Analytics III-24
Table 27: European Recent Past, Current & Future Analysis
for Brachytherapy Devices by Geographic Region - France,
Germany, Italy, UK, Spain, Russia, and Rest of Europe
Markets Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2013 through 2020 (includes
corresponding Graph/Chart) III-24
Table 28: European Historic Review for Brachytherapy Devices
by Geographic Region - France, Germany, Italy, UK, Spain,
Russia, and Rest of Europe Markets Independently Analyzed
with Annual Sales Figures in US$ Thousand for Years 2006
through 2012 (includes corresponding Graph/Chart) III-25
Table 29: European 15-Year Perspective for Brachytherapy
Devices by Geographic Region - Percentage Breakdown of
Revenues for France, Germany, Italy, UK, Spain, Russia, and
Rest of Europe Markets for Years 2006, 2014 & 2020 (includes
corresponding Graph/Chart) III-26
4a. FRANCE III-27
A.Market Analysis III-27
A Focus on the Prostate Brachytherapy Market III-27
B.Market Analytics III-27
Table 30: French Recent Past, Current & Future Analysis for
Brachytherapy Devices Market Analyzed with Annual Sales
Figures in US$ Thousand for Years 2013 through 2020
(includes corresponding Graph/Chart) III-27
Table 31: French Historic Review for Brachytherapy Devices
Market Analyzed with Annual Sales Figures in US$ Thousand
for Years 2006 through 2012 (includes corresponding
Graph/Chart) III-28
4b. GERMANY III-29
A.Market Analysis III-29
Strategic Corporate Developments III-29
Eckert & Ziegler Strahlen & Medizintechnik AG - A Key Player III-29
B.Market Analytics III-30
Table 32: German Recent Past, Current & Future Analysis for
Brachytherapy Devices Market Analyzed with Annual Sales
Figures in US$ Thousand for Years 2013 through 2020
(includes corresponding Graph/Chart) III-30
Table 33: German Historic Review for Brachytherapy Devices
Market Analyzed with Annual Sales Figures in US$ Thousand
for Years 2006 through 2012 (includes corresponding
Graph/Chart) III-31
4c. ITALY III-32
Market Analysis III-32
Table 34: Italian Recent Past, Current & Future Analysis for
Brachytherapy Devices Market Analyzed with Annual Sales
Figures in US$ Thousand for Years 2013 through 2020
(includes corresponding Graph/Chart) III-32
Table 35: Italian Historic Review for Brachytherapy Devices
Market Analyzed with Annual Sales Figures in US$ Thousand
for Years 2006 through 2012 (includes corresponding
Graph/Chart) III-33
4d. UNITED KINGDOM III-34
A.Market Analysis III-34
UK Prostate Brachytherapy Market - An Overview III-34
Strategic Corporate Development III-34
B.Market Analytics III-35
Table 36: The UK Recent Past, Current & Future Analysis for
Brachytherapy Devices Market Analyzed with Annual Sales
Figures in US$ Thousand for Years 2013 through 2020
(includes corresponding Graph/Chart) III-35
Table 37: The UK Historic Review for Brachytherapy Devices
Market Analyzed with Annual Sales Figures in US$ Thousand
for Years 2006 through 2012 (includes corresponding
Graph/Chart) III-36
4e. SPAIN III-37
Market Analysis III-37
Table 38: Spanish Recent Past, Current & Future Analysis for
Brachytherapy Devices Market Analyzed with Annual Sales
Figures in US$ Thousand for Years 2013 through 2020
(includes corresponding Graph/Chart) III-37
Table 39: Spanish Historic Review for Brachytherapy Devices
Market Analyzed with Annual Sales Figures in US$ Thousand
for Years 2006 through 2012 (includes corresponding
Graph/Chart) III-38
4f. RUSSIA III-39
Market Analysis III-39
Table 40: Russian Recent Past, Current & Future Analysis for
Brachytherapy Devices Market Analyzed with Annual Sales
Figures in US$ Thousand for Years 2013 through 2020
(includes corresponding Graph/Chart) III-39
Table 41: Russian Historic Review for Brachytherapy Devices
Market Analyzed with Annual Sales Figures in US$ Thousand
for Years 2006 through 2012 (includes corresponding
Graph/Chart) III-40
4g. REST OF EUROPE III-41
A.Market Analysis III-41
Strategic Corporate Developments III-41
Nucletron BV (Netherlands) - Select Player III-41
B.Market Analytics III-42
Table 42: Rest of Europe Recent Past, Current & Future
Analysis for Brachytherapy Devices Market Analyzed with
Annual Sales Figures in US$ Thousand for Years 2013 through
2020 (includes corresponding Graph/Chart) III-42
Table 43: Rest of Europe Historic Review for Brachytherapy
Devices Market Analyzed with Annual Sales Figures in US$
Thousand for Years 2006 through 2012 (includes corresponding
Graph/Chart) III-43
5. ASIA-PACIFIC III-44
A.Market Analysis III-44
Growing Medical Tourism in Asia-Pacific Bodes Well for the
Brachytherapy Market III-44
Sirtex Medical Limited (Australia) - A Review III-44
B.Market Analytics III-45
Table 44: Asia-Pacific Recent Past, Current & Future
Analysis for Brachytherapy Devices by Geographic Region -
China, India, and Rest of Asia-Pacific Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2013 through 2020 (includes corresponding Graph/Chart) III-45
Table 45: Asia-Pacific Historic Review for Brachytherapy
Devices by Geographic Region - China, India, and Rest of
Asia-Pacific Markets Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2006 through 2012
(includes corresponding Graph/Chart) III-46
Table 46: Asia-Pacific 15-Year Perspective for Brachytherapy
Devices by Geographic Region - Percentage Breakdown of
Revenues for China, India, and Rest of Asia-Pacific Markets
for Years 2006, 2014 & 2020 (includes corresponding
Graph/Chart) III-47
6. THE MIDDLE EAST III-48
Market Analysis III-48
Table 47: The Middle East Recent Past, Current & Future
Analysis for Brachytherapy Devices Market Analyzed With
Annual Sales Figures in US$ Thousand for Years 2013 through
2020 (includes corresponding Graph/Chart) III-48
Table 48: The Middle East Historic Review for Brachytherapy
Devices Market Analyzed with Annual Sales Figures in US$
Thousand for Years 2006 through 2012 (includes corresponding
Graph/Chart) III-49
7. LATIN AMERICA III-50
Market Analysis III-50
Table 49: Latin American Recent Past, Current & Future
Analysis for Brachytherapy Devices by Geographic Region -
Brazil and Rest of Latin America Markets Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years
2013 through 2020 (includes corresponding Graph/Chart) III-50
Table 50: Latin American Historic Review for Brachytherapy
Devices by Geographic Region - Brazil and Rest of Latin
America Markets Independently Analyzed with Annual Sales
Figures in US$ Thousand for Years 2006 through 2012
(includes corresponding Graph/Chart) III-51
Table 51: Latin American 15-Year Perspective for
Brachytherapy Devices by Geographic Region - Percentage
Breakdown of Revenues for Brazil and Rest of Latin America
Markets for Years 2006, 2014 & 2020 (includes corresponding
Graph/Chart) III-52
IV. COMPETITIVE LANDSCAPE
Total Companies Profiled: 36 (including Divisions/Subsidiaries - 41)
The United States (26)
Canada (1)
Europe (12)
- Germany (4)
- The United Kingdom (2)
- Rest of Europe (6)
Asia-Pacific (Excluding Japan) (2)
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