Global Drug Adherence Enhancement Market: Devices & Applications (2018-2030)

DUBLIN, Dec. 11, 2018 /PRNewswire/ --

The "Drug Adherence Enhancement Market: Devices and Applications, 2018-2030" report has been added to ResearchAndMarkets.com's offering.

This report features an extensive study of the current landscape and future outlook of the growing market for smart medication adherence devices that are either already commercialized or under development. This burgeoning field presently offers a lot of opportunities to innovation-driven start-ups and investors.

Poor adherence to prescribed medications is a growing concern in the healthcare industry and is believed to be associated with negative health outcomes, inflated medical expenses, loss in productivity and, in certain cases, proves fatal as well. It has been estimated that, of the 4 billion annual prescriptions filled by the retailers in the US, approximately 50% are not taken by patients in accordance to physicians' instructions.

According to the US Centers for Disease Control and Prevention (CDC), failure to comply to prescribed treatment regimens has been identified as the cause of 125,000 premature deaths, up to 69% of all rehospitalizations, and results in approximately USD 100-300 billion worth of avoidable annual healthcare spending. Further, the US pharmaceutical industry alone is estimated to suffer a loss of approximately USD 188 billion per year, due to low adherence to prescribed medications.

Lack of compliance with therapy is particularly prevalent among elderly patients suffering from chronic clinical conditions, such as cardiovascular disorders, metabolic disorders (e.g., diabetes), neurological and central nervous system related disorders (e.g., multiple sclerosis and Parkinson's disease) and respiratory disorders (e.g., asthma and chronic obstructive pulmonary disease).

It is estimated that overall cost of treatment for non-adherent patients is at least twice as high as patients who adhere to recommended therapy regimens. Studies have demonstrated that every one percent improvement in medication adherence can help the US healthcare industry save up to USD 2 billion, resulting in an increase in pharmaceutical revenues by ~USD 4 billion.

As a result, several strategies have been/are being developed by pharmaceutical developers and healthcare providers to improve medication adherence. Such initiatives have been strengthened owing to the availability of connected devices and other digital solutions, which allow patients/healthcare providers to closely monitor and improve drug adherence.

Example Highlights:

1. Currently, over 60 smart drug delivery devices are either commercially available or are under development for improving adherence to medication. More than 50% of these devices are smart inhalers or smart injectors. Examples of smart inhalers and smart injectors include (in alphabetical order, no selection criteria) 3M Intelligent Control Inhaler (3M), BETACONNECT (Medicom Innovation Partner), eMDI (H&T Presspart), Flexi-Q eMU-P and Flexi-Q eMU-C (Elcam Drug Delivery Device), GoCap (Common Sensing), Propeller (Propeller Health), SMARTTURBO, SMARTTOUCH and SMARTTOUCH AV (Adherium), and SmartPilot and YpsoMate Smart (Ypsomed).
2. In addition, there are close to 75 smart accessory devices that are either commercially available or are under development. Of these, over 40% are smart medication dispensers. Noteworthy examples of such products include (in alphabetical order, no selection criteria)Evondos E300 (Evondos), HERO (HERO Health), Maya and Jon (MedMinder Systems), MedaCube (PharmaAdva) and Philips Medido (Philips), Pillo (Pillo Health) and SIMPLEMED+ (Vaica).
3. Around 70% of the companies that are involved in the development of smart drug delivery systems and smart accessory systems are small-sized players/start-ups (having less than 50 employees). Examples of such companies include (in alphabetical order, no selection criteria) Aerobit Health, Airbrio, Arthur Health, Cognita Labs, CuePath Innovation, DayaMed, etectRx, MedMinder Systems, PharmRight, Popit, Portal Instruments, and Wealth Taxi.
4. Over 50 compliance packaging systems are available to promote medication adherence among patients suffering from chronic clinical conditions; these include blister packs, pouches and dose cups. Companies engaged in the development of such products include (in alphabetical order, no selection criteria) Dispill-USA (Dispill Multi-dose Packaging), Keystone Folding Box (Ecoslide-RX, Key-Pak and Key-Pak Plus), Omnicell (Opti-Pak and SureMed), Parata Systems (Parata PASS Pack) and TCGRx (AdherePac and AdhereCard)
5. Many standalone mobile applications are also available for improving compliance to prescribed therapeutic regimens. As of July 2018, over 200 such mobile applications, having user ratings of more than four, were available on Google Play Store. It is worth mentioning that more than 70% smart drug delivery and accessory devices that we came across have a supporting mobile application.
6. Close to 180 partnerships have been inked between various stakeholders within the industry over the last few years; of these, over 100 collaborations were signed since 2016. Most of the deals that we came across were product development agreements (53%), signed between players to include new features in their products or advance their development programs. Examples of recently established deals include collaborations between Ypsomed and JDRF (August 2018), Adherium and Vitalus Health (August 2018), Amiko Digital Health and Luz Sade (July 2018), Becton Dickinson and Helmer Scientific (June 2018), Common Sensing and Flex (May 2018), and Compliance Meds Technologies and Oracle Health Sciences (April 2018),
7. Since 2001, nearly USD 2.5 billion has been invested in companies operating in the field of medication adherence. Interestingly, close to half of the total amount (USD 1.1 billion) was raised between 2015 and August 2018, indicating the rising interest of strategic investors in this domain. Examples of players that have managed to secure capital investments in multiple rounds include Proteus Digital Health, NantHealth, Tandem Diabetes Care, Propeller Health and Cellnovo.
8. The drug adherence market is expected to grow at an annualized rate of more than 15.4% between 2018 and 2030. It is important to highlight that North America (primarily the US) and Europe currently capture the largest share of the overall market. This is followed by Asia-Pacific and the rest of the world. As the industry matures, we expect the market in Asia-Pacific to grow owing to the sizable user base in the region.

Key Topics Covered

1. Preface

1.1. Scope of the Report
1.1. Research Methodology
1.2. Chapter Outlines

2. Executive Summary

3. Introduction
3.1. Medication Non-Adherence: A National Epidemic
3.2. Medication Adherence and its Measurement
3.3. Types of Medication Non-Adherence
3.4. Improving Medication Adherence
3.5. Key Initiatives to Improve Medication Adherence

4. Smart Drug Delivery Devices: Current Market Landscape
4.1. Chapter Overview
4.2. Smart Drug Delivery Devices: Overall Market Landscape

5. Smart Accessory Devices And Packaging Systems: Current Market Landscape
5.1. Chapter Overview
5.2. Smart Accessory Devices: Overall Market Landscape
5.3. Compliance Packaging Systems: Overall Market Landscape

6. Regulatory Landscape For Connected Drug Delivery Systems
6.1. Chapter Overview
6.2. North America
6.3. Europe
6.4. Latin America
6.5. Asia-Pacific
6.6. Middle East
6.7. Connected Devices: Demonstrating Safety, Effectiveness and Performance
6.8. Connected Devices: Ensuring Security of Data Captured

7. Drug Delivery Devices: Company Profiles
7.1. Chapter Overview
7.2. Adherium
7.3. BIOCORP
7.4. nGageIT Digital Health
7.5. Proteus Digital Health
7.6. SOOIL Development
7.7. Ypsomed

8. Accessory Devices: Company Profiles
8.1. Chapter Overview
8.2. AARDEX Group
8.3. Information Mediary
8.4. MedMinder Systems
8.5. Philips
8.6. Tinylogics
8.7. Vaica

9. Case Studies
9.1. Chapter Overview
9.2. Case Study I: Diabetes
9.3. Case Study II: Asthma
9.4. Case Study III: Rheumatoid Arthritis

10. Product Competitiveness Analysis
10.1. Chapter Overview
10.2. Methodology
10.3. Overall Product Competitiveness Analysis

11. Funding and Investment Analysis
11.1. Chapter Overview
11.2. Types of Funding
11.3. Drug Adherence Enhancement Market: Funding and Investment Analysis
11.4. Concluding Remarks

12. Partnerships and Collaborations
12.1. Chapter Overview
12.2. Partnership Models
12.3. Drug Adherence Enhancement Market: List of Partnerships and Collaborations

13. Medication Adherence With Mobile Applications
13.1. Chapter Overview
13.2. The Increasing Trend of Mobile Applications in Healthcare Industry
13.3. USFDA Regulations for Mobile Medical Applications
13.4. List of Mobile Applications for Improving Medication Adherence
13.5. Medication Adherence with Mobile Applications: Clinical Research Evidence

14. Market Forecast
14.1. Chapter Overview
14.2. Forecast Methodology and Key Assumptions
14.3. Global Drug Adherence Enhancement Market
14.4. Global Drug Adherence Enhancement Market: Distribution by Geography, 2018-2030 (By Value)
14.5. Global Drug Adherence Enhancement Market: Distribution by Type of Product and Geography (By Value)
14.6. Global Drug Adherence Enhancement Market: Distribution by Type of Product (By Volume)
14.7. Global Drug Adherence Enhancement Market: Distribution by Therapeutic Area and Geography (By Value)
14.8. Global Drug Adherence Enhancement Market: Distribution by Therapeutic Area and Geography (By Volume)
14.9. Global Drug Adherence Enhancement Market: Distribution by Route of Drug Administration and Geography (By Value)
14.10. Global Drug Adherence Enhancement Market: Distribution by Route of Drug Administration and Geography (By Volume)

15. Conclusion
15.1. Poor Adherence to Therapies for the Treatment of Chronic Disorders Poses a Significant Economic Burden on the Healthcare Industry
15.2. Presently, Several Players are Developing IoT-Enabled / Connected Devices for Improving Medication Adherence; Majority of these are Small-sized Companies based in the US
15.3. Increasing Financial Support from Various Investors is Indicative of Future Opportunities related to Novel Strategies for Medication Adherence Improvement
15.4. Players have Entered into Strategic Collaborations to Support the Development of their Smart Products
15.5. Availability of Standalone, as well as Companion Mobile Applications, is Expected to Provide a More Integrated Approach for Improving Adherence
15.6. With Increasing Focus on Improving Therapy Efficacy and Alleviating Healthcare Burden, the Overall Market is Anticipated to Witness Steady Growth

16. Executive Insights
16.1. Chapter Overview
16.2. AARDEX Group
16.3. AceAge
16.4. AdhereTech
16.5. Amiko Digital Health
16.6. Cognita Labs
16.7. etectRx
16.8. PharmAdva
16.9. Popit Technologies
16.10. Wealth Taxi
16.11 Small-sized Company

Companies Featured

• 3M
• 5AM Ventures
• 7wire Ventures
• 91streets Media Technologies
• AARDEX Group
• AARP
• Abbott
• Abiogenix
• AceAge
• Acintyo
• Acta Distribution
• ActiveCare
• Adams Street Partners
• AdhereTech
• Adherium
• Administracin Nacional de Medicamentos, Alimentosy Tecnologa Mdica
• Advent Venture Partners
• Aerobit Health
• AeroSonix
• Aguettant
• Agncia Nacional de Vigilncia Sanitria (National Health Surveillance Agency)
• Air Liquide Healthcare
• AIRBRIO
• Airnest
• Allscripts
• Altran
• Amarutek
• Amazon
• AMC Health
• American Academy of Allergy, Asthma and Immunology
• American Heart Association
• Amerigroup
• Amgen
• Amiko Digital Health
• ANTARGYAN CLOUDWORKS
• ApnaCare India
• Apollo Diabetes Care Management
• Apolotus Health Solution
• Apoteket
• App Singularity
• AppAttic
• Appgraid Apps
• AppQuik
• AppTrailz
• Aptar Pharma
• Area9 Innovation
• Arthur Health
• Artmedus
• ARTORG Center
• AS PHARM SOFT
• Asheville Angels
• Asho Soft Tech
• Asset Management Ventures
• Asthma and Respiratory Foundation New Zealand
• AstraZeneca
• AT&T
• Aterica Digital Health
• August Faller Group
• Auriga Partners
• Australasian Medical & Scientific
• Austrian Chamber of Pharmacists
• Automated Security Alert
• Aventyn
• Avery Dennison Medical Solutions
• Avnet Integrated Solutions
• Baviux
• Bayer
• Becton Dickinson
• BERG
• Bigfoot Biomedical
• BioAdvance
• BioAssist
• BIOCORP
• BioMark Health
• BioScience Managers
• BIVA
• Blackberry
• BlackPearls
• Blueprint Health
• Boehringer Ingelheim
• Bosch
• Brain Tech
• Brainovations Education Excellence
• Breed Reply
• Butterfly Ventures
• C Square Info Solutions
• C-Square Info Solutions
• C3HealthLink
• caiocrol
• California HealthCare Foundation
• California Highlands Addiction Treatment
• Cambridge Consultants
• Cambridge Enterprise
• Canada Innovation Acceleration Investment
• Capital Angels
• Capital Royalty Partners II
• Cardinal Health
• CareCentra
• CareConsult
• CareZone
• Catalent Pharma Solutions
• Celgene
• Cellnovo
• Cenduit
• Centers for Disease Control and Prevention
• Centers for Medicare & Medicaid Services
• Central Drugs Standard Control Organization
• Centric Health
• Chalmers Ventures
• CheckTheMeds Technology
• Children's Hospital of Philadelphia
• China Food and Drug Administration
• CHORDAS
• Chronicare
• Cigna Health Insurance
• Cincinnati Children's Hospital Medical Center
• Circadian Design
• Clifton R Farris
• CML Advocates Network
• Cognita Labs
• Cognitive Healthcare
• Cohero Health
• Colbert Packaging
• Comisin Federal para la Proteccin contra Riesgos Sanitarios
• Common Sensing
• Community Care Network of Virginia
• Companion Medical
• Compliance Meds Technologies
• Confrrie Clinique
• Connecticut Children's Medical Center
• Core Mobile
• Credit Agricole Private Equity
• Crux Product Design
• CSL Behring
• CUCO Health
• CuePath Innovation
• Curatio
• Curis
• Cyft
• DayaMed
• Debiotech
• Decision Machines
• DeepBench
• Delphi Ventures
• Desert Oasis Healthcare
• DeskShare
• Dexcom
• Diabeloop
• Diasend
• Digital Pharmacist
• Diplomat Pharmacy
• Disetronic Group
• Dispill-USA
• DistriMedic
• DocRoSh Health
• Domain Associates
• Dosecast
• DoseCue
• DoseSmart
• DOTh Solutions
• Douglas Pharmaceuticals
• Drug Package
• Duke University
• DYN Diagnostics
• E Ink
• EcoloPharm
• Edmond de Rothschild
• Elcam Drug Delivery Devices (E3D)
• Eli Lilly
• Elkstone Capital Partners
• EMedStore Pharma IT
• emocha Mobile Health
• Emperra E-Health Technologies
• Enable Injections
• Enercon Technologies
• EnvoyHealth
• Essex Woodlands
• etectRx
• ETHIO APPS
• Eularis
• European Investment Bank
• European Medicines Agency
• Evalan
• Everwell Health Solutions
• Everwin Precision Technology
• Evondos
• Excell Partners
• Experts in Communications and Connectivity Technology (ECCT)
• Express Scripts
• Fagor Healthcare
• Fedefarma
• Fidelity International
• FindAir
• Fletcher Spaght Ventures
• Flex
• Forbion Capital Partners
• Frost & Sullivan
• GalileoMD
• Gecko Health Innovations
• GenieMD
• Genome BC
• GIS Strategic Ventures
• GlaxoSmithKline
• Global Emerging Markets Group
• Gloria Pharmaceuticals
• GlucoRx
• GoodCare Pharma
• GoodRx
• GoodVent Beteiligungsmanagement
• GoSmart
• H&T Presspart
• H&Y Apps
• Hackensack Meridian Health
• HAP Innovations
• Haselmeier
• HCL Technologies
• Health Bot
• Health Canada
• Health Care Originals
• Health Department of Oslo
• Health Mission
• Health Monitor
• Health's Angel
• HealthBeacon
• Healthbox
• HealthCare Ventures
• Healthcom
• Healtheoz
• Healthio
• HealthPrize Technologies
• Heitkamp & Thumann Group
• Helmer Scientific
• Hepatitis Victoria
• HERO Health
• Hexoskin
• Hikma Ventures
• Home Diagnostics
• HP Labs
• HTC
• Human API
• Humana
• IAP Labs
• IDEAL LIFE
• ImageWare Systems
• ImagineCare
• Immunex
• Information Mediary
• Innospence
• Innovation Zed
• INRange Systems
• Inspirit Innovations
• Insulin Pump Hellas
• Intelligent Devices SEZC
• Intelligent Product Solutions
• Intent Solutions
• International Diabetes Federation
• International Federation of Pharmaceutical Manufacturers and Associations
• Intigate Technologies
• Investitionsbank des Landes Brandenburg
• Irody
• IRWAA
• iSense
• ITmedicus
• Itochu
• IVAX
• Jabil
• Janssen Pharmaceutica
• JDRF
• Jiangsu Delfu Medical Device
• Jones Packaging
• Joslin Diabetes Center
• Journey Health Labs
• JVS Technologies
• K-svets
• Kaiser Permanente Ventures
• KCRise Fund
• Keystone Folding Box
• Konkuk University
• Korl Medical Center
• Kreos Capital
• Kuwait Investment Authority
• Life Integrating Technologies and Experiences (LITE)
• Life Sciences Angel Network
• LifeMatters
• LloydsPharmacy
• Lohmann Therapie Systeme
• lool Ventures
• Lowcountry Angels
• LoyAlerts
• LSDinfotech
• Luz Sade
• M Ventures
• M2M Datasmart
• Maangata Apps
• Maccabi Healthcare Services
• Mail-Meds
• Maj Invest Equity
• Manchac Technologies
• Mango Health
• Manrex
• Manyeta
• MAP Health Management
• Marketaro
• MassChallenge
• Maxerence
• McKesson
• MeadWestvaco
• MedApps
• MedControl Technologies
• MedCrypt
• Medexpert
• Medical International Research
• Medical Research Institute of New Zealand
• Medical Specialties Australia
• Medication Solutions
• Medicine-On-Time
• Medico Pak
• Medicom Innovation Partner
• MedicPen
• Medimate
• Medipense
• Medisafe
• MedMinder Systems
• Medocity
• MedPak Pharmacy
• MedReady
• MedSmart
• Medtronic
• Medtrum
• MENA Apps
• Merck
• Metro Health
• Mevia
• MicroHealth
• Ministry of Food and Drug Safety
• Ministry of Health, Labour and Welfare
• MivaTek Smart Connect
• Molina Healthcare
• Montuno Software
• Mount Sinai Health System
• Movi
• MphRx
• Multiframes
• Mylan
• MyMeds
• MyTherapy
• NantHealth
• Nath IT Solutions
• National Competent Authority
• National Consumers League
• National Institute of Mental Health (NIMH)
• National Institutes of Health
• Navia Life Care
• NaviMed
• NBGI Ventures
• NECTEC
• Nemera
• NESTA
• Nestl Health Science
• New Directions Technology Consulting
• New World Health
• New Zealand Medical & Scientific
• NexusLink Services
• nGageIT Digital Medicine
• Noble International
• NOPII
• Novalab Ibrica
• Novartis
• Novo Nordisk
• Now Healthcare Group
• NPS MedicineWise
• Octopus Ventures
• Office of the National Coordinator for Health Information Technology Omnicell
• Omron Healthcare
• One Drop
• Onward Care Technologies
• Oracle Health Sciences
• Orbita
• ORI Healthcare Fund
• Otsuka Pharmaceutical
• Oxford Finance
• Oyster Capital Partners
• P5 Health Ventures
• Palladio Group
• Parata Systems
• Partners HealthCare
• PatientPartner
• PBJ Capital
• Pear Therapeutics
• Pegasystems
• Peppermint VenturePartners
• PhableCare
• Pharmacell Medication Systems
• Pharmaceutical and Medical Devices Agency
• PharmAdva
• PharmaSens
• PharmRight
• Philips
• Phillips-Medisize
• Phoenix Healthcare
• Picomol Healthcare
• PillDrill
• Pillo Health
• PillPack
• Pitango Venture Capital
• Play-it Health
• PMA Pharmacy
• Poliweb Graphics
• Popit
• Portal Instruments
• Practo
• Prescription Notification Group
• Prescription Solutions
• ProCare Rx
• Propeller Health
• Proteus Digital Health
• PRPL
• Qualcomm Life
• Quantum Pharmaceutical
• Quido Healthcare Services
• QuiO Technologies
• Quizora Media
• Raffles Medical Group
• Ramtin Software Solutions
• Raneem Technologies
• Recovery Centers of America
• RemindTrac
• Renata
• Research Institute of the McGill University Health Centre
• Resolve Digital Health
• Respia
• Rex Medical
• Risk Cooperative
• Robert Bosch Venture Capital
• Roche
• RockTenn
• Rubin Medical
• RxAdvance
• RxNetworks
• RXVIP Concierge
• Safeguard Scientifics
• Safeway
• Sagentia
• Samsung
• Samsung NEXT
• Sanner Group
• Sanofi
• Sanofi-Sunrise
• Saudi Food and Drug Authority
• Schreiner MediPharm
• SCRA Technology
• Second Technology Capital Investors
• SentiCare
• Seoul National University
• Serendipity Partners
• SHL Group
• Silicon Valley Bank
• Simplified APP Solutions
• Sino Portfolio
• Sinwho
• SmarterHealth TechServe
• Smartgateways
• Smiths Medical
• Smooth Apps Studio
• SMRxT
• Social Capital
• Soft Industry Alliance
• Sonceboz
• SOOIL Development
• South Carolina Angel Network
• Spartanburg Angels
• Spring Ridge Ventures
• Sprint
• Spyzar Studios
• SR One
• St. Helena Health
• St. Jude Medical
• STAAR Alert
• Sunrise Labs
• SuperAndroidApp
• Swanhill Capital
• Syqe Medical
• Takeda Pharmaceutical
• Tandem Diabetes Care
• TCGRx
• Techizer Tech Solutions
• Tekes
• TerraNovita
• Teva Pharmaceutical
• The Carlyle Group
• The Cyto Cord Group
• The Finnish Funding Agency for Technology and Innovation
• The Kroger
• Therapeutic Goods Administration
• Three Leaf Ventures
• Tidepool
• Tillotts Pharma
• TimerCap
• Tinylogics
• Tonghua Dongbao Pharmaceutical
• TowerView Health
• TPG Biotech
• Triad HealthCare Network
• Tricella
• Trinnovate Ventures
• TriVentures
• TypeZero Technologies
• UNICUS HealthReach
• United Family Healthcare
• United States Food and Drug Administration
• UnitedHealthcare
• University of Arkansas for Medical Sciences
• University of Cambridge
• University of Pittsburgh Medical Center
• University of Toronto
• Urtech Manufacturing
• Vaica
• Valtronic
• Vectura Group
• Verizon Investments
• Virbac
• Vishnu Global Services
• Vitalus Health
• Walgreens
• Waterline Ventures
• Wcre8tive App Developer
• Wealth Taxi
• Web Coast Apps
• Welkin Health
• West Pharmaceutical Services
• WestRock
• Whisper Arts
• WMM
• World Allergy Organization
• World Health Organization
• WorldMedic
• Wyeth-Ayerst Pharmaceuticals
• Xcenda
• Xhale
• Ximedica
• XINK Laboratories
• YOURmeds
• YPSOMED
• Zaffre Investments
• Zibdy
• Zipit Wireless

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