LONDON, Feb. 3, 2016 /PRNewswire/ -- According to the new report "Global Life Science Microscopy Devices Market Assessment & Forecast 2015 - 2019" by Spearhead Acuity Business Research & Consulting Group, Structural Biology research was the greatest revenue generating application area within the life science microscopy devices market. In 2014, the segment raised a demand of US$ 707.4 million worth microscopy equipment which translates into a share of 39.9%.
Microscopy devices were immediately imbued within medical and healthcare research after the world realized the presence of microbiota. As the world reeled under various diseases, microscopes quickly found application in identification of pathogens. For over 2-3 centuries, people used and developed only optical microscopes; however limitations of optical microscopes due to technological barrier for resolution power, people from around the world began developing electron microscopes by 1900s. Unlike optical devices, electron microscopes utilized electron beams to image. Siemens built the first electron microscope under the guidance of Rudenberg followed by several companies and institutes such as General Electric, Farrand Optical Company, JEOL, Akashi, Hitachi, Shimadzu, and Zeiss. Manufacturers from United States and Japan were at the forefront of this new advanced technology and continue to remain at the helm of new innovations in microimaging even today.
The study of understanding biological organisms, functioning of surfaces and parts of plant or animal life, staining or dyeing of biological specimens has been of prime importance to the life science research industry. Structural biology comprises the study of organizational structure of microorganisms, animal and plant life at a microscopic level. Structural biology includes cytobiology, histology and microbiology. Understanding tissues, organs and life processes is crucial to finding weaknesses for combating against microbial diseases. Dramatic improvements in experimental methods and computational techniques of electron microscopy has enabled the technology to expand into a powerful and diverse collection of methods that allow the visualization of the structure and the dynamics of an extraordinary range of biological entities at resolution spanning from molecular (about 2–3 nm) to near atomic level.
Disease pathology uses a variety of different microscopy technologies for application. New approaches include cryo-SEM applications and environmental SEM (ESEM), staining techniques and processing applications combining embedding and resin-extraction for imaging with high resolution SEM, and advances in immuno-labeling. Viral diseases today regularly use immune-fluorescence for identification and testing and visual confirmation still continues to be a mainstay in this area. This makes optical microscopy the most prominent choice of devices to be used. Digitization of pathology labs has greatly increased the demand of digital microscopes. Digital microscopes can stich images together to give a better picture and expand the view for faster diagnoses.
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