Global Markets for Reagents for Chromatography -- Focus on Liquid Chromatography

NEW YORK, Oct. 11, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Global Markets for Reagents for Chromatography -- Focus on Liquid Chromatography

http://www.reportlinker.com/p01009674/Global-Markets-for-Reagents-for-Chromatography----Focus-on-Liquid-Chromatography.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Diagnostics

INTRODUCTION

STUDY OBJECTIVES

The purpose of this study, conducted by BCC, is to offer a synopsis of the current characteristics of the global market for chromatography reagents in order to forecast its future. The key intent is to provide an extensive analysis of the current market and the future trends for the chromatography reagents market. The report offers analysis on the market size, market leaders, and factors affecting the market of chromatography reagents from the perspective of its end users, which includes the pharma and biotech, food and beverages, environmental agencies and other sectors.

This report investigates current and future strategies within the chromatography techniques and reagents market. The report takes a close look at the market's inventiveness, its setbacks and future needs. The comparisons, usage and the advantages and disadvantages of different types of chromatography products and reagents are also covered in this report.

A comprehensive analysis of chromatography reagents sales is given, broken down by regions—North America, Europe and emerging markets. Sales figures are forecast for the five-year period from 2012 through 2017.

REASONS FOR DOING THIS STUDY

Chromatography techniques and reagents are being used extensively in pharmaceutical and biotechnology industries in the development of pure drug compounds. The primary usage of chromatography techniques is for quality assurance of drug products wherein chromatography separation techniques can, in some cases, assure up to 99.9% purity level and can reveal the impurities to 0.1% or even smaller. These separations or analysis techniques use chromatography reagents for the measurement of the drug purity, which has led to the growing market of the reagents. The study thus focuses on the usage of these reagents in various industries across the global markets.

Most of the techniques of chromatography and their reagents are discussed in this report. The fast-changing scenarios and developmental landscape of various technologies in the market justify focusing on this segment. Along with the end users—pharmaceutical and biotech, food and beverage, environmental agencies and other industries—merger and acquisition and collaborations of companies are also covered in this report. This study also discusses the strengths and weaknesses of each reagent type/technology in light of new technologies, growing competition and changing customer needs.

CONTRIBUTIONS OF THE STUDY AND ITS AUDIENCE

This study contributes to knowledge and understanding of market growth and setbacks for chromatography reagents from the manufacturer and end user perspectives. Pharmaceutical, biochemical, chemical, petrochemical, food and beverage industries, clinics, forensics and environmental agencies will find this study to be of interest.

SCOPE OF THE STUDY

The scope of this study comprises the markets of reagents of chromatography along with various chromatography techniques. BCC analyzes each market; the different types of chromatographic techniques and reagents; the regulatory aspects; the end users of the chromatographic reagents and market projections, its market leaders and market share. The study also offers details of technological refinements including the latest trends and developments.

METHODOLOGY

Both primary and secondary research methodologies were used in preparing this study. BCC carried out a comprehensive literature search that included technical newsletters, journals, technical blogs and research papers as well as many other sources. The data were collected through interviews and correspondence with various pharmaceutical, biotechnical, food and beverage and environment experts. Projections were based on estimates such as the current number of end users, potential end users, likely unit prices, rates of consumption and market trends.

INFORMATION SOURCES

BCC surveyed various companies within the industry to obtain data for this study. They were reputed manufacturers and end users of chromatographic reagents in pharmaceutical, chemical, biotechnology, food & beverages and other relevant industries. BCC spoke with officials within the industry, consulted newsletters, company literature, product literature, technical articles, journals, indexes and abstracts. Exhaustive investigations of databases by key terminology were done. In addition, data were compiled from current financial, trade and governmental sources.

ABOUT THE AUTHOR

The study has been carried out by a team of professionals in the biotechnology industry. The project manager for this project is Shalini S. Dewan, who holds a master's degree in pharmaceutical chemistry and has more than 14 years of industry experience. Shalini was awarded a Gold Medal by the Prime Minister of India for her work and has worked with top companies in India and in the U.S. Some of her other reports with BCC are: Reagents for Chromatography; Spectroscopy, An Enduring Market; Advanced Drug Delivery Systems, Technologies and Global Markets; Orthopedic Drugs, Implants and Devices; Medical Imaging Reagents and Analysis Equipment; Pharmaceutical Regulatory Industry; The Dynamic Media, Sera and Reagent Market in Biotechnology; Contract Pharmaceutical Manufacturing, Research and Packaging: Global Markets; Chiral Technology: Global Markets; Autacoids and Related Drugs: Technologies and Global Markets; Contraceptives: Technologies and Global Markets; Liver Disease Treatments: The Global Market; Hormone Replacement Therapies and Other Hormone Therapies: Global Markets; Cardiovascular Medicine: Diagnostics, Drugs and Devices; and Cancer Therapies: Technologies and Global Markets.

TABLE OF CONTENTS

CHAPTER 1 INTRODUCTION 1

STUDY OBJECTIVES 1

REASONS FOR DOING THIS STUDY 1

CONTRIBUTIONS OF THE STUDY AND ITS AUDIENCE 1

SCOPE OF THE STUDY 2

METHODOLOGY 2

INFORMATION SOURCES 2

ABOUT THE AUTHOR 2

RELATED BCC RESEARCH REPORTS 3

BCC ON-LINE SERVICES 3

DISCLAIMER 3

CHAPTER 2 SUMMARY 5

SUMMARY TABLE GLOBAL REVENUES FOR THE REAGENTS USED IN DIFFERENT TYPES OF

CHROMATOGRAPHY TECHNIQUES, THROUGH 2017 ($ MILLIONS) 6

SUMMARY FIGURE GLOBAL REVENUES FOR THE REAGENTS USED IN DIFFERENT TYPES

OF CHROMATOGRAPHY TECHNIQUES, 2010-2017 ($ MILLIONS) 6

CHAPTER 3 OVERVIEW 9

DEFINITIONS 9

REAGENTS FOR CHROMATOGRAPHY 9

TYPES OF REAGENTS 10

Silylation Reagents 10

TABLE 1 ADVANTAGES AND DISADVANTAGES OF SILYLATION 10

TABLE 2 SILYLATION REAGENTS 10

Alkylation Reagents 11

TABLE 3 ADVANTAGES AND DISADVANTAGES OF ALKYLATION 11

TABLE 4 ALKYLATING REAGENTS 12

Acylation Reagents 12

TABLE 5 ADVANTAGES AND DISADVANTAGES OF ACYLATION 12

TABLE 6 ACYLATING REAGENTS 12

Ion-Pairing Reagents 13

TABLE 7 ADVANTAGES AND DISADVANTAGES OF ION-PAIRING CHROMATOGRAPHY 13

TABLE 8 ION-PAIRING REAGENTS 14

Solvents 14

TABLE 9 EXAMPLES OF SOLVENTS USED IN CHROMATOGRAPHY 14

Buffers 15

TABLE 10 BUFFERS USED IN CHROMATOGRAPHY 15

Adsorbents 15

TABLE 11 ADSORBENTS USED IN GAS-SOLID AND LIQUID-SOLID CHROMATOGRAPHY 16

CLASSIFICATION OF CHROMATOGRAPHY 16

TYPES OF CHROMATOGRAPHY WITH THE USE REAGENTS AND THEIR APPLICATIONS 16

GAS CHROMATOGRAPHY (GC) 16

TABLE 12 ADVANTAGES AND DISADVANTAGES OF GAS CHROMATOGRAPHY 17

Reagents Used in Gas Chromatography 17

TABLE 13 REAGENTS USED IN GAS CHROMATOGRAPHY 17

MST054A - Global Markets for Reagents for Chromatography -- Focus on Liquid Chromatography

Copyright © BCC Research, Wellesley MA USA, Website: www.bccresearch.com

TOPIC PAGE NO.

Applications of Gas Chromatography 18

TABLE 14 APPLICATIONS OF GAS CHROMATOGRAPHY 18

LIQUID CHROMATOGRAPHY (LC) 18

Paper Chromatography (PC) 19

TABLE 15 ADVANTAGES AND DISADVANTAGES OF PAPER CHROMATOGRAPHY 19

Applications of Paper Chromatography 19

Thin Layer Chromatography (TLC) 19

TABLE 16 ADVANTAGES AND DISADVANTAGES OF THIN LAYER CHROMATOGRAPHY 20

TABLE 17 REAGENTS USED IN THIN LAYER CHROMATOGRAPHY 20

Applications of Thin Layer Chromatography 20

High-Performance Liquid Chromatography (HPLC) 20

Ultra High-Performance Liquid Chromatography (UHPLC) 21

Fast Protein Liquid Chromatography (FPLC) 21

TABLE 18 ADVANTAGES AND DISADVANTAGES OF HIGH-PERFORMANCE LIQUID

CHROMATOGRAPHY 21

Reagents used in HPLC 21

TABLE 19 REAGENTS USED IN HPLC CHROMATOGRAPHY 21

Applications of HPLC 22

TABLE 20 APPLICATIONS OF HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY 22

SORPTION CHROMATOGRAPHY 22

Adsorption Chromatography 22

TABLE 21 ADVANTAGES AND DISADVANTAGES OF ADSORPTION CHROMATOGRAPHY 22

Reagents Used in Adsorption Chromatography 23

TABLE 22 REAGENTS USED IN ADSORPTION CHROMATOGRAPHY 23

Applications of Adsorption Chromatography 23

Partition Chromatography 23

Reverse Phase Partition Chromatography 23

Normal Phase Partition Chromatography 23

TABLE 23 ADVANTAGES AND DISADVANTAGES OF PARTITION CHROMATOGRAPHY 24

Reagents used in Partition Chromatography 24

Applications of Adsorption Chromatography 24

SIZE EXCLUSION CHROMATOGRAPHY 24

TABLE 24 ADVANTAGES AND DISADVANTAGES OF SIZE EXCLUSION CHROMATOGRAPHY 24

Reagents Used in Size Exclusion Chromatography 25

Applications of Size Exclusion Chromatography 25

ION EXCHANGE CHROMATOGRAPHY 25

Cation Exchange 25

Anion exchange 25

TABLE 25 ADVANTAGES AND DISADVANTAGES OF ION EXCHANGE CHROMATOGRAPHY 25

Reagents Used in Ion Exchange Chromatography 26

TABLE 26 REAGENTS USED IN ION EXCHANGE CHROMATOGRAPHY 26

Applications of Ion Exchange Chromatography 26

ION PAIR CHROMATOGRAPHY 26

TABLE 27 ADVANTAGES AND DISADVANTAGES OF ION PAIR CHROMATOGRAPHY 26

Reagents Used in Ion Pair Chromatography 27

TABLE 28 REAGENTS USED IN ION PAIR CHROMATOGRAPHY 27

Applications of Ion Pair Chromatography 27

AFFINITY CHROMATOGRAPHY 27

TABLE 29 ADVANTAGES AND DISADVANTAGES OF AFFINITY CHROMATOGRAPHY 27

Reagents Used in Affinity Chromatography 28

TABLE 30 REAGENTS USED IN AFFINITY CHROMATOGRAPHY 28

Applications of Affinity Chromatography 28

COLUMN CHROMATOGRAPHY 28

TABLE 31 ADVANTAGES AND DISADVANTAGES OF COLUMN CHROMATOGRAPHY 28

Reagents Used in Column Chromatography 29

TABLE 32 REAGENTS USED IN COLUMN CHROMATOGRAPHY 29

Applications of Column Chromatography 29

OPEN BED OR PLANAR CHROMATOGRAPHY 29

TABLE 33 ADVANTAGES AND DISADVANTAGES OF OPEN BED OR PLANAR

CHROMATOGRAPHY 29

Reagents Used in Open Bed or Planar Chromatography 30

TABLE 34 REAGENTS USED IN PLANAR CHROMATOGRAPHY 30

Applications of Open Bed or Planar Chromatography 30

SIMULATED MOVING BED CHROMATOGRAPHY (SMB) 30

TABLE 35 ADVANTAGES AND DISADVANTAGES OF SIMULATED MOVING BED

CHROMATOGRAPHY 31

Reagents Used in SMB Chromatography 31

TABLE 36 REAGENTS USED IN SMB CHROMATOGRAPHY 31

Applications of SMB Chromatography 31

TABLE 37 APPLICATIONS OF SMB CHROMATOGRAPHY 31

SUPERCRITICAL FLUID CHROMATOGRAPHY (SFC) 31

TABLE 38 ADVANTAGES AND DISADVANTAGES OF SUPERCRITICAL FLUID

CHROMATOGRAPHY 32

Reagents Used in Supercritical Fluid Chromatography 32

TABLE 39 REAGENTS USED IN SFC CHROMATOGRAPHY 32

TABLE 40 CRITICAL PROPERTIES OF COMMONLY USED SCFS (SUPERCRITICAL FLUID

SOLVENTS) 32

Applications of Supercritical Fluid Chromatography 33

CAPILLARY ELECTROPHORESIS 33

TABLE 41 ADVANTAGES AND DISADVANTAGES OF CAPILLARY ELECTROPHORESIS 33

Reagents Used in Capillary Electrophoresis 33

TABLE 42 REAGENTS USED IN CAPILLARY ELECTROPHORESIS 34

Applications of Capillary Electrophoresis 34

TABLE 43 APPLICATIONS OF CAPILLARY ELECTROPHORESIS 34

CHAPTER 4 REGULATORY ASPECTS 36

INTRODUCTION 36

TABLE 44 CLASSES OF SOLVENTS AS PER FDA 37

ACETONE 38

CHLOROFORM 38

BENZENE 38

METHANOL 38

PHENOL 38

PYRIDINE 39

TOLUENE 39

1,2,3-TRICHLOROPROPANE 39

METHYLENE CHLORIDE 39

2 -BUTANONE 40

CHAPTER 5 NEW DEVELOPMENTS 42

CHAPTER 6 GLOBAL MARKETS 46

MARKETS BY TECHNOLOGY 46

MARKET OVERVIEW 46

MARKET REVENUE 47

TABLE 45 GLOBAL REVENUES FOR REAGENTS USED IN DIFFERENT TYPES OF

CHROMATOGRAPHY TECHNIQUES, THROUGH 2017 ($ MILLIONS) 47

FIGURE 1 GLOBAL REVENUES FOR REAGENTS USED IN DIFFERENT TYPES OF

CHROMATOGRAPHY TECHNIQUES, 2010-2017 ($ MILLIONS) 47

MARKET SHARE 48

TABLE 46 ESTIMATED MARKET SHARE OF REAGENTS BY TECHNOLOGY, 2011 (%) 49

FIGURE 2 ESTIMATED MARKET SHARE OF REAGENTS BY TECHNOLOGY, 2011 (%) 49

MARKETS BY TYPES OF REAGENTS 49

MARKET OVERVIEW 50

MARKET REVENUE 51

TABLE 47 GLOBAL SALES OF MAJOR CLASSES OF REAGENTS USED IN CHROMATOGRAPHY,

THROUGH 2017 ($ MILLIONS) 51

FIGURE 3 GLOBAL SALES OF MAJOR CLASSES OF REAGENTS USED IN CHROMATOGRAPHY,

2010-2017 ($ MILLIONS) 51

MARKET SHARE 52

TABLE 48 ESTIMATED MARKET SHARE OF MAJOR CLASSES OF REAGENTS USED IN

CHROMATOGRAPHY, 2011 (%) 53

FIGURE 4 ESTIMATED MARKET SHARE OF MAJOR CLASSES OF REAGENTS USED IN

CHROMATOGRAPHY, 2011 (%) 53

MARKET BY REGION 54

MARKET OVERVIEW 54

MARKET REVENUE FOR SOLVENTS 55

TABLE 49 SALES OF SOLVENTS USED IN CHROMATOGRAPHY BY REGION, THROUGH 2017

($ MILLIONS) 56

FIGURE 5 SALES OF SOLVENTS USED IN CHROMATOGRAPHY, 2010-2017 ($ MILLIONS) 56

MARKET REVENUE FOR CHEMICALS 56

TABLE 50 SALES OF CHEMICALS USED IN CHROMATOGRAPHY BY REGION, THROUGH 2017

($ MILLIONS) 57

FIGURE 6 SALES OF CHEMICALS USED IN CHROMATOGRAPHY BY REGION, 2010-2017 ($

MILLIONS) 57

MARKET REVENUE FOR GASES 57

TABLE 51 SALES OF GASES USED IN CHROMATOGRAPHY BY REGION, THROUGH 2017 ($

MILLIONS) 58

FIGURE 7 SALES OF GASES USED IN CHROMATOGRAPHY BY REGION, 2010-2017 ($

MILLIONS) 58

MARKET REVENUE FOR ADSORBENTS 58

TABLE 52 SALES OF ADSORBENTS USED IN CHROMATOGRAPHY BY REGION, THROUGH

2017 ($ MILLIONS) 59

FIGURE 8 SALES OF ADSORBENTS USED IN CHROMATOGRAPHY BY REGION, 2010-2017 ($

MILLIONS) 59

MARKET REVENUE FOR MEMBRANES 59

TABLE 53 SALES OF MEMBRANES USED IN CHROMATOGRAPHY BY REGION, THROUGH

2017 ($ MILLIONS) 60

FIGURE 9 SALES OF MEMBRANES USED IN CHROMATOGRAPHY BY REGION, 2010-2017 ($

MILLIONS) 60

MARKET REVENUE FOR CAPILLARIES 60

TABLE 54 SALES OF CAPILLARIES USED IN CHROMATOGRAPHY BY REGION, THROUGH

2017 ($ MILLIONS) 61

FIGURE 10 SALES OF CAPILLARIES USED IN CHROMATOGRAPHY BY REGION, 2010-2017 ($

MILLIONS) 61

MARKET REVENUE FOR PLATES 61

TABLE 55 SALES OF PLATES USED IN CHROMATOGRAPHY BY REGION, THROUGH 2017 ($

MILLIONS) 62

FIGURE 11 SALES OF PLATES USED IN CHROMATOGRAPHY BY REGION, 2010-2017 ($

MILLIONS) 62

MARKET REVENUE FOR FLUIDS 62

TABLE 56 SALES OF FLUIDS AND REAGENTS USED IN SUPERCRITICAL FLUID

CHROMATOGRAPHY BY REGION, THROUGH 2017 ($ MILLIONS) 63

FIGURE 12 SALES OF FLUIDS AND REAGENTS USED IN SUPERCRITICAL FLUID

CHROMATOGRAPHY BY REGION, 2010-2017 ($ MILLIONS) 63

MARKET SHARE 63

TABLE 57 ESTIMATED NORTH AMERICAN DEMAND FOR MAJOR TYPES OF REAGENTS USED

IN CHROMATOGRAPHY, 2011 (%) 64

FIGURE 13 ESTIMATED NORTH AMERICAN DEMAND FOR MAJOR TYPES OF REAGENTS

USED IN CHROMATOGRAPHY, 2011 (%) 64

MARKET BY INDUSTRIAL END USERS 64

PHARMACEUTICAL AND BIOTECHNOLOGY 65

Market Overview 65

TABLE 58 GLOBAL CONSUMPTION OF THE REAGENTS (BY TECHNOLOGY) USED IN

PHARMACEUTICAL INDUSTRY, THROUGH 2017 ($ MILLIONS) 66

FIGURE 14 GLOBAL CONSUMPTION OF THE REAGENTS (BY TECHNOLOGY) USED IN

PHARMACEUTICAL INDUSTRY, 2010-2017 ($ MILLIONS) 66

Market Share 67

TABLE 59 GLOBAL DEMAND OF VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN PHARMACEUTICAL COMPANIES, 2011 (%) 68

FIGURE 15 GLOBAL DEMAND OF VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN PHARMACEUTICAL COMPANIES, 2011 (%) 68

FOOD AND BEVERAGE 68

Market Overview 69

TABLE 60 GLOBAL CONSUMPTION OF REAGENTS (BY TECHNOLOGY) USED IN THE FOOD

AND BEVERAGE INDUSTRY, THROUGH 2017 ($ MILLIONS) 69

FIGURE 16 GLOBAL CONSUMPTION OF REAGENTS (BY TECHNOLOGY) USED IN FOOD AND

BEVERAGE INDUSTRY, 2010-2017 ($ MILLIONS) 70

Market Share 71

TABLE 61 GLOBAL DEMAND FOR VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN FOOD AND BEVERAGE COMPANIES, 2011 (%) 71

FIGURE 17 GLOBAL DEMAND FOR VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN FOOD AND BEVERAGE COMPANIES, 2011 (%) 71

ENVIRONMENTAL AGENCIES 72

Market Overview 72

TABLE 62 GLOBAL CONSUMPTION OF REAGENTS (BY TECHNOLOGY) USED IN

ENVIRONMENTAL AGENCIES, THROUGH 2017 ($ MILLIONS) 73

FIGURE 18 GLOBAL CONSUMPTION OF REAGENTS (BY TECHNOLOGY) USED IN

ENVIRONMENTAL AGENCIES, 2010-2017 ($ MILLIONS) 74

Market Share 74

TABLE 63 GLOBAL DEMAND FOR VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN ENVIRONMENTAL AGENCIES, 2011 (%) 75

FIGURE 19 GLOBAL DEMAND FOR VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN ENVIRONMENTAL AGENCIES, 2011 (%) 75

OTHERS 75

Market Overview 76

TABLE 64 GLOBAL CONSUMPTION OF REAGENTS (BY TECHNOLOGY) USED IN OTHER

INDUSTRIES, THROUGH 2017 ($ MILLIONS) 77

FIGURE 20 GLOBAL CONSUMPTION OF REAGENTS (BY TECHNOLOGY) USED IN OTHER

INDUSTRIES, 2010-2017 ($ MILLIONS) 77

Market Share 78

TABLE 65 GLOBAL DEMAND FOR VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN OTHER INDUSTRIES, 2011 (%) 78

FIGURE 21 GLOBAL DEMAND FOR VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN OTHER INDUSTRIES, 2011 (%) 78

CHAPTER 7 LIQUID CHROMATOGRAPHY REAGENTS - MARKET ANALYSIS 80

MARKET BY REAGENTS 80

MARKET OVERVIEW 80

MARKET REVENUE 81

TABLE 66 SALES OF REAGENTS IN LIQUID CHROMATOGRAPHY, THROUGH 2017 ($

MILLIONS) 81

FIGURE 22 SALES OF REAGENTS IN LIQUID CHROMATOGRAPHY, 2010-2017 ($ MILLIONS) 81

MARKET SHARE 81

TABLE 67 MARKET SHARE OF LIQUID REAGENTS BY TYPE, 2011 (%) 82

FIGURE 23 MARKET SHARE OF LIQUID REAGENTS BY TYPE, 2011 (%) 82

MARKET BY REGION 82

TABLE 68 SALES OF SOLVENTS USED IN LIQUID CHROMATOGRAPHY, THROUGH 2017 ($

MILLIONS) 83

FIGURE 24 SALES OF SOLVENTS USED IN LIQUID CHROMATOGRAPHY BY REGION,

2010-2017 ($ MILLIONS) 83

TABLE 69 SALES OF CHEMICALS USED IN LIQUID CHROMATOGRAPHY BY REGION,

THROUGH 2017 ($ MILLIONS) 84

FIGURE 25 SALES OF CHEMICALS USED IN LIQUID CHROMATOGRAPHY BY REGION,

2010-2017 ($ MILLIONS) 84

MARKET SHARE 85

TABLE 70 MARKET SHARE OF LIQUID REAGENTS BY REGION, 2011 (%) 85

FIGURE 26 MARKET SHARE OF LIQUID REAGENTS BY REGION, 2011 (%) 85

MARKET BY END USERS 85

PHARMACEUTICAL INDUSTRY 86

FOOD AND BEVERAGE INDUSTRY 87

ENVIRONMENTAL ANALYSIS 88

OTHERS 88

TABLE 71 CONSUMPTION OF REAGENTS BY END-USER INDUSTRIES IN LIQUID

CHROMATOGRAPHY, THROUGH 2017 ($ MILLIONS) 89

FIGURE 27 CONSUMPTION OF THE REAGENTS BY END-USER INDUSTRIES IN LIQUID

CHROMATOGRAPHY, 2010-2017 ($ MILLIONS) 90

MARKET SHARE 90

TABLE 72 MARKET SHARE OF LIQUID CHROMATOGRAPHY REAGENTS BY END USERS, 2011

(%) 91

FIGURE 28 MARKET SHARE OF LIQUID CHROMATOGRAPHY REAGENTS BY END USERS,

2011 (%) 91

MARKET LEADERS AND THEIR SHARES 91

TABLE 73 MARKET SHARE OF MANUFACTURERS/ SUPPLIERS OF LIQUID

CHROMATOGRAPHY REAGENTS, 2011 (%) 92

FIGURE 29 MARKET SHARE OF MANUFACTURERS/SUPPLIERS OF LIQUID

CHROMATOGRAPHY REAGENTS, 2011 (%) 92

CHAPTER 8 PATENT ANALYSIS 94

PATENTS BY YEAR 94

TABLE 74 NUMBER OF PATENTS BY YEAR, 2008-2012 (NO.) 94

FIGURE 30 NUMBER OF PATENTS BY YEAR, 2008-2012 (NO.) 94

PATENTS BY TYPE OF REAGENTS 95

TABLE 75 PATENTS BY TYPE FOR CHROMATOGRAPHY REAGENTS 2008-2012 (NUMBER OF

PATENTS) 95

FIGURE 31 PATENTS BY TYPE FOR CHROMATOGRAPHY REAGENTS 2008-2012 (NUMBER OF

PATENTS) 95

PATENTS BY TYPE OF CHROMATOGRAPHY 96

TABLE 76 PATENTS BY TYPE OF CHROMATOGRAPHY 2008-2012 (NUMBER OF PATENTS) 96

FIGURE 32 PATENTS BY TYPE OF CHROMATOGRAPHY 2008-2012 (NUMBER OF PATENTS) 97

PATENTS BY COUNTRY 97

TABLE 77 NUMBER OF U.S. PATENTS BY COUNTRY FOR CHROMATOGRAPHY REAGENTS,

2008–2012 98

FIGURE 33 NUMBER OF U.S. PATENTS BY COUNTRY FOR CHROMATOGRAPHY REAGENTS,

2008-2012 98

TABLE 78 PATENT SHARES BY COUNTRY FOR CHROMATOGRAPHY REAGENTS 2008-2012

(NO./%) 99

FIGURE 34 PATENT SHARES BY COUNTRY FOR CHROMATOGRAPHY REAGENTS, 2008-2012

(%) 99

PATENTS BY COMPANY 100

TABLE 79 NUMBER OF U.S. PATENTS BY COMPANY FOR CHROMATOGRAPHY REAGENTS,

2008-2012 101

PATENTS BY ASSIGNEE 101

TABLE 80 PATENTS BY ASSIGNEE FOR CHROMATOGRAPHY REAGENTS, 2008-2012 102

FIGURE 35 PATENTS BY ASSIGNEE FOR CHROMATOGRAPHY REAGENTS 2008-2012 102

CHAPTER 9 CURRENT SITUATION 104

CONSUMERS OF CHROMATOGRAPHY REAGENTS 104

PHARMACEUTICAL INDUSTRY 104

Drug Discovery 104

Drug Development 105

Purification and Isolation 105

Manufacturing and Quality Assurance/Quality Control (QA/QC) 105

Biopharmaceuticals 106

ENVIRONMENTAL AGENCIES 106

FOOD AND BEVERAGE 106

FOOD LABORATORIES 107

NUTRACEUTICAL INDUSTRY 107

CLINICS AND FORENSICS 108

MERGERS AND ACQUISITIONS/LATEST DEVELOPMENTS 108

FACTORS GOVERNING THE CHROMATOGRAPHY REAGENTS MARKET 110

INCREASE FOCUS ON PROTEIN PURIFICATION 110

INCREASED R&D EXPENDITURE 110

CURRENT MARKET DRIVERS 111

CHAPTER 10 COMPANY PROFILES 114

AGILENT TECHNOLOGIES 114

AVANTOR PERFORMANCE MATERIALS 114

BECKMAN COULTER, INC 115

BIO-RAD LABORATORIES, INC. 115

DANAHER CORPORATION 116

DIONEX CORPORATION 116

GE HEALTHCARE LIFE SCIENCES 117

HELENA LABORATORIES 117

HICHROM LIMITED 118

HOEFER INC. 119

LONZA GROUP LTD. 119

MILLIPORE CORPORATION 119

NACALAI TESQUE 120

REGIS TECHNOLOGIES 120

SEBIA 121

SERVA ELECTROPHORESIS GMBH 122

SIGMA-ALDRICH CORPORATION 122

THERMO FISHER SCIENTIFIC INC. 123

TOSOH BIOSCIENCES LLC 123

VWR INTERNATIONAL 124

W. R. GRACE & CO. 124

CHAPTER 11 APPENDIX I-ABBREVIATIONS 127

LIST OF TABLES

SUMMARY TABLE GLOBAL REVENUES FOR THE REAGENTS USED IN DIFFERENT TYPES OF

CHROMATOGRAPHY TECHNIQUES, THROUGH 2017 ($ MILLIONS) 6

TABLE 1 ADVANTAGES AND DISADVANTAGES OF SILYLATION 10

TABLE 2 SILYLATION REAGENTS 10

TABLE 3 ADVANTAGES AND DISADVANTAGES OF ALKYLATION 11

TABLE 4 ALKYLATING REAGENTS 12

TABLE 5 ADVANTAGES AND DISADVANTAGES OF ACYLATION 12

TABLE 6 ACYLATING REAGENTS 12

TABLE 7 ADVANTAGES AND DISADVANTAGES OF ION-PAIRING CHROMATOGRAPHY 13

TABLE 8 ION-PAIRING REAGENTS 14

TABLE 9 EXAMPLES OF SOLVENTS USED IN CHROMATOGRAPHY 14

TABLE 10 BUFFERS USED IN CHROMATOGRAPHY 15

TABLE 11 ADSORBENTS USED IN GAS-SOLID AND LIQUID-SOLID CHROMATOGRAPHY 16

TABLE 12 ADVANTAGES AND DISADVANTAGES OF GAS CHROMATOGRAPHY 17

TABLE 13 REAGENTS USED IN GAS CHROMATOGRAPHY 17

TABLE 14 APPLICATIONS OF GAS CHROMATOGRAPHY 18

TABLE 15 ADVANTAGES AND DISADVANTAGES OF PAPER CHROMATOGRAPHY 19

TABLE 16 ADVANTAGES AND DISADVANTAGES OF THIN LAYER CHROMATOGRAPHY 20

TABLE 17 REAGENTS USED IN THIN LAYER CHROMATOGRAPHY 20

TABLE 18 ADVANTAGES AND DISADVANTAGES OF HIGH-PERFORMANCE LIQUID

CHROMATOGRAPHY 21

TABLE 19 REAGENTS USED IN HPLC CHROMATOGRAPHY 21

TABLE 20 APPLICATIONS OF HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY 22

TABLE 21 ADVANTAGES AND DISADVANTAGES OF ADSORPTION CHROMATOGRAPHY 22

TABLE 22 REAGENTS USED IN ADSORPTION CHROMATOGRAPHY 23

TABLE 23 ADVANTAGES AND DISADVANTAGES OF PARTITION CHROMATOGRAPHY 24

TABLE 24 ADVANTAGES AND DISADVANTAGES OF SIZE EXCLUSION CHROMATOGRAPHY 24

TABLE 25 ADVANTAGES AND DISADVANTAGES OF ION EXCHANGE CHROMATOGRAPHY 25

TABLE 26 REAGENTS USED IN ION EXCHANGE CHROMATOGRAPHY 26

TABLE 27 ADVANTAGES AND DISADVANTAGES OF ION PAIR CHROMATOGRAPHY 26

TABLE 28 REAGENTS USED IN ION PAIR CHROMATOGRAPHY 27

TABLE 29 ADVANTAGES AND DISADVANTAGES OF AFFINITY CHROMATOGRAPHY 27

TABLE 30 REAGENTS USED IN AFFINITY CHROMATOGRAPHY 28

TABLE 31 ADVANTAGES AND DISADVANTAGES OF COLUMN CHROMATOGRAPHY 28

TABLE 32 REAGENTS USED IN COLUMN CHROMATOGRAPHY 29

TABLE 33 ADVANTAGES AND DISADVANTAGES OF OPEN BED OR PLANAR

CHROMATOGRAPHY 29

TABLE 34 REAGENTS USED IN PLANAR CHROMATOGRAPHY 30

TABLE 35 ADVANTAGES AND DISADVANTAGES OF SIMULATED MOVING BED

CHROMATOGRAPHY 31

TABLE 36 REAGENTS USED IN SMB CHROMATOGRAPHY 31

TABLE 37 APPLICATIONS OF SMB CHROMATOGRAPHY 31

TABLE 38 ADVANTAGES AND DISADVANTAGES OF SUPERCRITICAL FLUID

CHROMATOGRAPHY 32

TABLE 39 REAGENTS USED IN SFC CHROMATOGRAPHY 32

TABLE 40 CRITICAL PROPERTIES OF COMMONLY USED SCFS (SUPERCRITICAL FLUID

SOLVENTS) 32

TABLE 41 ADVANTAGES AND DISADVANTAGES OF CAPILLARY ELECTROPHORESIS 33

TABLE 42 REAGENTS USED IN CAPILLARY ELECTROPHORESIS 34

TABLE 43 APPLICATIONS OF CAPILLARY ELECTROPHORESIS 34

TABLE 44 CLASSES OF SOLVENTS AS PER FDA 37

TABLE 45 GLOBAL REVENUES FOR REAGENTS USED IN DIFFERENT TYPES OF

CHROMATOGRAPHY TECHNIQUES, THROUGH 2017 ($ MILLIONS) 47

TABLE 46 ESTIMATED MARKET SHARE OF REAGENTS BY TECHNOLOGY, 2011 (%) 49

TABLE 47 GLOBAL SALES OF MAJOR CLASSES OF REAGENTS USED IN CHROMATOGRAPHY,

THROUGH 2017 ($ MILLIONS) 51

TABLE 48 ESTIMATED MARKET SHARE OF MAJOR CLASSES OF REAGENTS USED IN

CHROMATOGRAPHY, 2011 (%) 53

TABLE 49 SALES OF SOLVENTS USED IN CHROMATOGRAPHY BY REGION, THROUGH 2017 ($

MILLIONS) 56

TABLE 50 SALES OF CHEMICALS USED IN CHROMATOGRAPHY BY REGION, THROUGH 2017

($ MILLIONS) 57

TABLE 51 SALES OF GASES USED IN CHROMATOGRAPHY BY REGION, THROUGH 2017 ($

MILLIONS) 58

TABLE 52 SALES OF ADSORBENTS USED IN CHROMATOGRAPHY BY REGION, THROUGH 2017

($ MILLIONS) 59

TABLE 53 SALES OF MEMBRANES USED IN CHROMATOGRAPHY BY REGION, THROUGH 2017

($ MILLIONS) 60

TABLE 54 SALES OF CAPILLARIES USED IN CHROMATOGRAPHY BY REGION, THROUGH 2017

($ MILLIONS) 61

TABLE 55 SALES OF PLATES USED IN CHROMATOGRAPHY BY REGION, THROUGH 2017 ($

MILLIONS) 62

TABLE 56 SALES OF FLUIDS AND REAGENTS USED IN SUPERCRITICAL FLUID

CHROMATOGRAPHY BY REGION, THROUGH 2017 ($ MILLIONS) 63

TABLE 57 ESTIMATED NORTH AMERICAN DEMAND FOR MAJOR TYPES OF REAGENTS USED

IN CHROMATOGRAPHY, 2011 (%) 64

TABLE 58 GLOBAL CONSUMPTION OF THE REAGENTS (BY TECHNOLOGY) USED IN

PHARMACEUTICAL INDUSTRY, THROUGH 2017 ($ MILLIONS) 66

TABLE 59 GLOBAL DEMAND OF VARIOUS CHROMATOGRAPHIC REAGENTS (BY TECHNOLOGY)

IN PHARMACEUTICAL COMPANIES, 2011 (%) 68

TABLE 60 GLOBAL CONSUMPTION OF REAGENTS (BY TECHNOLOGY) USED IN THE FOOD

AND BEVERAGE INDUSTRY, THROUGH 2017 ($ MILLIONS) 69

TABLE 61 GLOBAL DEMAND FOR VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN FOOD AND BEVERAGE COMPANIES, 2011 (%) 71

TABLE 62 GLOBAL CONSUMPTION OF REAGENTS (BY TECHNOLOGY) USED IN

ENVIRONMENTAL AGENCIES, THROUGH 2017 ($ MILLIONS) 73

TABLE 63 GLOBAL DEMAND FOR VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN ENVIRONMENTAL AGENCIES, 2011 (%) 75

TABLE 64 GLOBAL CONSUMPTION OF REAGENTS (BY TECHNOLOGY) USED IN OTHER

INDUSTRIES, THROUGH 2017 ($ MILLIONS) 77

TABLE 65 GLOBAL DEMAND FOR VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN OTHER INDUSTRIES, 2011 (%) 78

TABLE 66 SALES OF REAGENTS IN LIQUID CHROMATOGRAPHY, THROUGH 2017 ($ MILLIONS) 81

TABLE 67 MARKET SHARE OF LIQUID REAGENTS BY TYPE, 2011 (%) 82

TABLE 68 SALES OF SOLVENTS USED IN LIQUID CHROMATOGRAPHY, THROUGH 2017 ($

MILLIONS) 83

TABLE 69 SALES OF CHEMICALS USED IN LIQUID CHROMATOGRAPHY BY REGION,

THROUGH 2017 ($ MILLIONS) 84

TABLE 70 MARKET SHARE OF LIQUID REAGENTS BY REGION, 2011 (%) 85

TABLE 71 CONSUMPTION OF REAGENTS BY END-USER INDUSTRIES IN LIQUID

CHROMATOGRAPHY, THROUGH 2017 ($ MILLIONS) 89

TABLE 72 MARKET SHARE OF LIQUID CHROMATOGRAPHY REAGENTS BY END USERS, 2011

(%) 91

TABLE 73 MARKET SHARE OF MANUFACTURERS/ SUPPLIERS OF LIQUID CHROMATOGRAPHY

REAGENTS, 2011 (%) 92

TABLE 74 NUMBER OF PATENTS BY YEAR, 2008-2012 (NO.) 94

TABLE 75 PATENTS BY TYPE FOR CHROMATOGRAPHY REAGENTS 2008-2012 (NUMBER OF

PATENTS) 95

TABLE 76 PATENTS BY TYPE OF CHROMATOGRAPHY 2008-2012 (NUMBER OF PATENTS) 96

TABLE 77 NUMBER OF U.S. PATENTS BY COUNTRY FOR CHROMATOGRAPHY REAGENTS,

2008–2012 98

TABLE 78 PATENT SHARES BY COUNTRY FOR CHROMATOGRAPHY REAGENTS 2008-2012

(NO./%) 99

TABLE 79 NUMBER OF U.S. PATENTS BY COMPANY FOR CHROMATOGRAPHY REAGENTS,

2008-2012 101

TABLE 80 PATENTS BY ASSIGNEE FOR CHROMATOGRAPHY REAGENTS, 2008-2012 102

LIST OF FIGURES

SUMMARY FIGURE GLOBAL REVENUES FOR THE REAGENTS USED IN DIFFERENT TYPES OF

CHROMATOGRAPHY TECHNIQUES, 2010-2017 ($ MILLIONS) 6

FIGURE 1 GLOBAL REVENUES FOR REAGENTS USED IN DIFFERENT TYPES OF

CHROMATOGRAPHY TECHNIQUES, 2010-2017 ($ MILLIONS) 47

FIGURE 2 ESTIMATED MARKET SHARE OF REAGENTS BY TECHNOLOGY, 2011 (%) 49

FIGURE 3 GLOBAL SALES OF MAJOR CLASSES OF REAGENTS USED IN CHROMATOGRAPHY,

2010-2017 ($ MILLIONS) 51

FIGURE 4 ESTIMATED MARKET SHARE OF MAJOR CLASSES OF REAGENTS USED IN

CHROMATOGRAPHY, 2011 (%) 53

FIGURE 5 SALES OF SOLVENTS USED IN CHROMATOGRAPHY, 2010-2017 ($ MILLIONS) 56

FIGURE 6 SALES OF CHEMICALS USED IN CHROMATOGRAPHY BY REGION, 2010-2017 ($

MILLIONS) 57

FIGURE 7 SALES OF GASES USED IN CHROMATOGRAPHY BY REGION, 2010-2017 ($

MILLIONS) 58

FIGURE 8 SALES OF ADSORBENTS USED IN CHROMATOGRAPHY BY REGION, 2010-2017 ($

MILLIONS) 59

FIGURE 9 SALES OF MEMBRANES USED IN CHROMATOGRAPHY BY REGION, 2010-2017 ($

MILLIONS) 60

FIGURE 10 SALES OF CAPILLARIES USED IN CHROMATOGRAPHY BY REGION, 2010-2017 ($

MILLIONS) 61

FIGURE 11 SALES OF PLATES USED IN CHROMATOGRAPHY BY REGION, 2010-2017 ($

MILLIONS) 62

FIGURE 12 SALES OF FLUIDS AND REAGENTS USED IN SUPERCRITICAL FLUID

CHROMATOGRAPHY BY REGION, 2010-2017 ($ MILLIONS) 63

FIGURE 13 ESTIMATED NORTH AMERICAN DEMAND FOR MAJOR TYPES OF REAGENTS USED

IN CHROMATOGRAPHY, 2011 (%) 64

FIGURE 14 GLOBAL CONSUMPTION OF THE REAGENTS (BY TECHNOLOGY) USED IN

PHARMACEUTICAL INDUSTRY, 2010-2017 ($ MILLIONS) 66

FIGURE 15 GLOBAL DEMAND OF VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN PHARMACEUTICAL COMPANIES, 2011 (%) 68

FIGURE 16 GLOBAL CONSUMPTION OF REAGENTS (BY TECHNOLOGY) USED IN FOOD AND

BEVERAGE INDUSTRY, 2010-2017 ($ MILLIONS) 70

FIGURE 17 GLOBAL DEMAND FOR VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN FOOD AND BEVERAGE COMPANIES, 2011 (%) 71

FIGURE 18 GLOBAL CONSUMPTION OF REAGENTS (BY TECHNOLOGY) USED IN

ENVIRONMENTAL AGENCIES, 2010-2017 ($ MILLIONS) 74

FIGURE 19 GLOBAL DEMAND FOR VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN ENVIRONMENTAL AGENCIES, 2011 (%) 75

FIGURE 20 GLOBAL CONSUMPTION OF REAGENTS (BY TECHNOLOGY) USED IN OTHER

INDUSTRIES, 2010-2017 ($ MILLIONS) 77

FIGURE 21 GLOBAL DEMAND FOR VARIOUS CHROMATOGRAPHIC REAGENTS (BY

TECHNOLOGY) IN OTHER INDUSTRIES, 2011 (%) 78

FIGURE 22 SALES OF REAGENTS IN LIQUID CHROMATOGRAPHY, 2010-2017 ($ MILLIONS) 81

FIGURE 23 MARKET SHARE OF LIQUID REAGENTS BY TYPE, 2011 (%) 82

FIGURE 24 SALES OF SOLVENTS USED IN LIQUID CHROMATOGRAPHY BY REGION, 2010-2017

($ MILLIONS) 83

FIGURE 25 SALES OF CHEMICALS USED IN LIQUID CHROMATOGRAPHY BY REGION,

2010-2017 ($ MILLIONS) 84

FIGURE 26 MARKET SHARE OF LIQUID REAGENTS BY REGION, 2011 (%) 85

FIGURE 27 CONSUMPTION OF THE REAGENTS BY END-USER INDUSTRIES IN LIQUID

CHROMATOGRAPHY, 2010-2017 ($ MILLIONS) 90

FIGURE 28 MARKET SHARE OF LIQUID CHROMATOGRAPHY REAGENTS BY END USERS, 2011

(%) 91

FIGURE 29 MARKET SHARE OF MANUFACTURERS/SUPPLIERS OF LIQUID

CHROMATOGRAPHY REAGENTS, 2011 (%) 92

FIGURE 30 NUMBER OF PATENTS BY YEAR, 2008-2012 (NO.) 94

FIGURE 31 PATENTS BY TYPE FOR CHROMATOGRAPHY REAGENTS 2008-2012 (NUMBER OF

PATENTS) 95

FIGURE 32 PATENTS BY TYPE OF CHROMATOGRAPHY 2008-2012 (NUMBER OF PATENTS) 97

FIGURE 33 NUMBER OF U.S. PATENTS BY COUNTRY FOR CHROMATOGRAPHY REAGENTS,

2008-2012 98

FIGURE 34 PATENT SHARES BY COUNTRY FOR CHROMATOGRAPHY REAGENTS, 2008-2012 (%) 99

FIGURE 35 PATENTS BY ASSIGNEE FOR CHROMATOGRAPHY REAGENTS 2008-2012 102

To order this report:

Diagnostics Industry: Global Markets for Reagents for Chromatography -- Focus on Liquid Chromatography

__________________________

Contact Nicolas: [email protected]

US: (805)-652-2626

Intl: +1 805-652-2626

SOURCE Reportlinker

21%

more press release views with 

Request a Demo