NEW YORK, Sept. 4, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:
Global Next Generation Sequencers Industry
http://www.reportlinker.com/p0960429/Global-Next-Generation-Sequencers-Industry.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Genomics
This report analyzes the worldwide markets for Next Generation Sequencers in US$ Million. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2010 through 2018. The report profiles 83 companies including many key and niche players such as Agilent Technologies, Inc., Ambry Genetics Corp., BioNano Genomics, Inc., Caliper Life Sciences, Inc., Covaris, Inc., F. Hoffman-La Roche Ltd., 454 Life Sciences, GenoLogics Life Sciences Software, Inc., Genomic Health, Inc., Geospiza, Inc., Helicos BioSciences Corporation, Illumina, Inc., Ingenuity Systems, Inc., IntegenX, Inc., Kapa Biosystems, Inc., Life Technologies Corporation, Nanostring Technologies, Inc., New England Biolabs, Inc., NuGen Technologies, Inc., and RainDance Technologies, Inc. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain.
I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-2
Quantitative Techniques & Analytics I-3
Product Definitions and Scope of Study I-3
II. EXECUTIVE SUMMARY
1. INDUSTRY OVERVIEW II-1
Next Generation Sequencers: A Prelude II-1
Current and Future Analysis II-1
Market Overview II-2
Key Application Areas of NGS II-2
Table 1: Global NGS Applications (2011): Percentage Breakdown
of Usage Share by End-Uses - Human Genome Research; Clinical
Service Providers; Microorganisms, Plant and Animal Genetic
Analysis and Molecular Diagnostics (includes corresponding
Graph/Chart) II-2
Market Constraints and Challenges II-3
Clinical Applications of NGS - A Review of the Present Scenario II-3
Competitive Landscape Worldwide II-4
Table 2: NGS Sequencing Market in North America (2011):
Percentage Share Breakdown by leading Players -
Illumina/Solexa; Life Technologies, Roche/454 and Helicos
(includes corresponding Graph/Chart) II-5
Table 3: North America Microarray Market in (2011):
Percentage Share Breakdown by leading Players - Illumina Bead
Array, Affymetrix, Agilent Microarray and Roche/NimbleGen
Microarray (includes corresponding Graph/Chart) II-5
Future Prospects II-5
2. KEY MARKET TRENDS II-6
Global Market for NGS Positioned to Witness Significant Growth II-6
Rapid Technological Advancements Enable Strong Market Penetration II-6
High Throughput and Enhanced Performance Keep Up the Momentum II-6
Price Deceleration of Sequencing Paves Way for Use in Clinical
Labs II-7
Novel NGS Applications in New Carriers Screening Study II-7
Crop Development Using NGS Shows Promise II-7
Issue of Data Analysis Still Looms Large II-8
Emergence of NGS in Laboratory Data Management II-8
3. TECHNOLOGY OVERVIEW II-10
Evolution of Next Generation Sequencing II-10
Sanger Sequencing (Dideoxy Sequencing) II-10
Important Factors to Consider Before Choosing NGS Platforms II-11
Select Emerging Next Generation Sequencing Techniques II-11
Nanopore Sequencing Technique II-11
VisiGen Biotechnologies Approach II-12
Present Next Generation Sequencing Platforms II-12
Sequencing by Synthesis II-12
454 Genome Sequencer FLX Instrument (Roche Applied Science) II-12
Illumina (Solexa) Genome Analyzer II-12
Ion Torrent System II-13
Single-molecule Sequencing II-13
Helicos Single-Molecule Sequencing Device, Heliscope™ II-13
PacBio RS SMS Platform II-14
RNA Sequencing Technique II-14
Single Molecule SMRT™ Sequencing II-14
Single Molecule Real Time (RNAP) Sequencing II-14
Sequencing by Ligation II-14
Applied Biosystems ABI SOLiD System II-14
Azco Biotech Polonator II-15
Comparison of Select Next Generation Sequencing Technologies II-15
4. NGS APPLICATION AREAS II-16
NGS in Personalized Medical Technologies II-16
Prognostic/Preventative Technology II-16
Predictive Technology II-17
Personalized Technology II-17
NGS in Crop Breeding and Genetics II-17
Applications of NGS Technologies in Crop Breeding II-18
Molecular Markers and Genome Variation for MAS II-18
Resequencing in Well-Characterized Species II-19
De novo Sequencing of Crop Species without Reference Sequences II-19
Association Mapping in Natural Populations II-19
Wide Crosses and Alien Introgression II-20
Nucleotide Polymorphisms and Gene Expressions inTranscriptomes II-20
Evolutionary Biology and Population Genetics II-20
Genome-wide and Organellar Assembly II-20
Epigenetic Modifications II-21
5. RECENT INDUSTRY ACTIVITY II-22
GenomeQuest Offers Grants to Six Laboratories for NGS Diagnostics II-22
Cofactor Genomics Partners with Intrepid Bioinformatics for
Genomic Viewer II-22
PerkinElmer Acquires Caliper Life Sciences II-23
PerkinElmer Takes Over Geospiza Inc II-23
Agilent Technologies Acquires BioSystem Development and Halo
Genomics II-23
IntegenX Acquires GenVault II-24
BioNanomatrix Undergoes Name Change to BioNano Genomics II-24
NuGEN Collaborates with 454 Life Sciences for Ovation® RNA-Seq
System II-24
BGI Secures Certified Service Provider Status from Agilent
Technologies II-24
NuGEN Technologies Signs Agreement with WaferGen Biosystems II-25
IMGM Procures Fluidigm Access Array™ System from Fluidigm
Corporation II-25
Partek Signs Distribution Agreement with Life Technologies II-26
Caliper Life Sciences and Yale University Ink Agreement for
Automation of NGS Workflows II-26
Helicos BioSciences Signs Amended Agreement with Arizona
Technology II-26
Diagenode and BGI Enter into Collaboration for NGS and
Epigenetics II-27
Caliper Life Sciences and Roche Ink Agreement II-27
BGI Europe and Exonhit Collaborate for Genome- Wide
SpliceArray Project II-27
GnuBIO to Offer Early Access Sequencing System to Montreal
Heart Institute II-28
Medicinal Genomics Sequences Genomes of Cannabis Indica II-28
Good Start Genetics™ Identifies Disease Causing Mutations for
Genetic Disorders II-29
Illumina and UNTHSC Ink Agreement for NGS in Forensic Genetics II-29
DNAnexus and Google Offer Solution for Researchers to Access
SRA Database II-29
Agilent Technologies Signs Agreement with Oxford Gene
Technology for NGS II-30
Fluidigm Selects Research Instruments as Distributor for
Thailand and Singapore II-30
RUCDR Deploys NGS Library Systems of NuGEN Technologies II-30
Ambry Genetics Selects EMC® Isilon® Scale-Out NAS II-31
Illumina and Siemens Healthcare Enter Into Partnership II-31
Ambry Chooses SureSelect Target Enrichment System of Agilent
Technologies II-32
NuGen Technologies and Geospiza Ink Agreement II-32
Illumina and GenoLogics Enter into Co-Selling Agreement II-32
RainDance Technologies Enters into Collaboration with 454 Life
Sciences II-33
RainDance Technologies Enters into Collaboration with Ambry
Genetics II-33
Caliper Life Sciences Signs Co-marketing Agreement with Covaris II-33
Caliper Life Sciences Enters into Exclusive Distribution
Agreement with Trinean II-33
NuGEN Technologies Enters into Co-Marketing Agreement with
Caliper Life Sciences II-34
Geospiza Inks License Agreement with PerkinElmer II-35
Ingenuity Systems Enters into Scientific Collaboration with
Erasmus Medical Center II-35
Ingenuity Systems and GenomeQuest Enter into Partnership II-35
Precision System Science and Nordiag Ink Development Agreement II-36
Illumina Takes Over Epicentre Biotechnologies II-36
Roche Enters into Partnership with IBM to Develop Nanopore NGS
System II-37
Broad Institute Takes Over Pippin Prep Automated DNA Size
Selection Systems II-37
ACGT Purchases Illumina's Next-Generation DNA Sequencing Systems II-37
BGI Purchases Illumina HiSeq 2000 Sequencing Systems II-37
Jackson Laboratory Cancer Center Enters into Collaboration
with GenoLogics II-37
Ingenuity Systems Collaborates with Geospiza II-38
GeneGo Collaborates with Omicsoft II-38
454 Life Sciences Enters into Global Co-Promotional Agreement
with Fluidigm II-38
Genomatix Software and Eurofins Enter into Exclusive Global
Cooperation II-39
BlueArc® to Collaborate with Illumina II-39
NuGEN Technologies and Takara Bio Ink Non-Exclusive Agreement II-39
AMDeC Inks Vendor Partnership Agreement with RainDance
Technologies II-40
Life Technologies Enters into Collaboration with Ignite
Institute for Individualized Health II-40
Kapa Biosystems Enters into Distribution Agreement with VWR
International II-40
NewGene Collaborates with Roche NimbleGen II-41
CapitalBio and Roche Diagnostics Sign Memorandum of Understanding II-41
Bio Scientific Selects Eureka Genomics II-42
Michael Smith Genome Sciences Center Chooses New England Biolabs II-42
Roche Collaborates with IBM Research II-42
RainDance Technologies Signs Strategic Agreement with Applied
Biosystems II-42
Caliper Life Sciences and Illumina Sign Co-Marketing Agreement II-43
Illumina Inks Co-marketing Agreement with Covaris II-43
Life Technologies Takes Over Ion Torrent II-43
Source BioScience Acquires imaGenes II-43
Dow AgroSciences Enters into Trait Development Agreement with
KeyGene II-44
Agilent Technologies Inks Co-Marketing Agreement with Covaris II-44
Percorso Life Sciences and Generation Biotech Ink
Commercialization Agreement II-45
BGI Collaborates with OpGen II-45
Agilent Technologies Signs Agreement with Life Technologies II-46
GenoLogics Life Sciences Software Enters into Collaboration
with Life Technologies II-46
Life Technologies Inks Definitive Agreement to Acquire BioTrove II-46
Beckman Coulter Inks Definitive Agreement to Acquire Cogenics
Division of Clinical Data II-46
CLC bio Commences Novel Expansion Phase for Distributing NGS
Solutions in Japan II-47
PREMAS Biotech Enters into Partnership Agreement with Synamatix II-47
Eureka Genomics and Glycos Biotechnologies Enter into
Collaboration II-47
Oxford Nanopore Technologies and Illumina Enter into Key
Strategic Alliance II-48
CLC bio to Introduce Turnkey Solution II-48
Applied Biosystems Introduces SOLiD™ Whole Transcriptome
Analysis Kit II-48
CLC bio Introduces Next Generation Sequencing Solutions II-48
CLC bio Launches Enterprise Solution for Analyzing Next
Generation Sequencing Data II-49
SeqWright Partners with PharmaGenoma II-49
GenoLogics Life Sciences Software Collaborates with CLC bio II-49
Cogenics and SinoGenoMax Enter into Partnership II-50
Agilent Technologies Collaborates with Applied Biosystems II-50
BaseClear to Provide CLC Genomics Workbench License to NGS
Data Customers II-50
BGI Chooses Agilent Technologies II-50
EMBL Buys Integrated Solution for NGS Data Analysis II-51
6. PRODUCT/SERVICE INTRODUCTIONS II-52
Bio Scientific Launches NEXTflex™ DNA, PCR-Free ChIP-Seq Modules II-52
Illumina Unveils HiSeq® 2500 Next-Generation Sequencing System II-52
Life Technologies Unveils Benchtop Ion Proton Sequencer In India II-52
454 Life Sciences Launches GS GType HLA Primer Sets II-53
Agilent Technologies Launches Custom Kits for SureSelect XT
Target Enrichment System II-53
RainDance Technologies Introduces HLASeq™ Research Screening
Panel II-53
Accelrys Launches NGS Collection for Pipeline Pilot II-54
RainDance Technologies Introduces DeepSeq™ FFPE Solution for
Rare Cancer Mutations II-54
AITbiotech Introduces Ion Torrent-Based NGS Services II-55
Illumina Launches TruSeq Custom Enrichment Kits and DesignStudio II-55
NuGEN Technologies Introduces Encore 384 Multiplex System II-56
454 Life Sciences Unveils GS FLX+ System II-56
Transgenomic Introduces Nuclear Mitome Test II-57
Oxford Gene Technology Introduces Next Generation Targeted
Sequencing II-57
Ambry Genetics Introduces Illumina MiSeq NGS Services II-57
Agilent Technologies Unveils Agilent 2000 TapeStation II-58
NuGEN Technologies Rolls Out NuGEN Encore® Products for Ion PGM™ II-58
Roche NimbleGen to Roll Out New Solutions II-58
RainDance Technologies Introduces ThunderStorm™ System II-59
Appistry Unveils Advanced RNA-Seq Solutions Series II-59
Boreal Genomics Unveils Aurora Nucleic Acid Purification System II-60
Caliper Life Sciences Introduces Automated TruSeq™ NGS Protocols II-60
GenoLogics Life Sciences Software Introduces Rapid Scripting™ API II-60
New England Biolabs Unveils NEBNext® Small RNA Sample
Preparation Reagents II-61
Illumina Launches MiSeq™ Personal Sequencing System II-61
Illumina Launches Next-Generation iSelect Custom Genotyping
Products II-61
PerkinElmer Introduces Next-Generation DNA Sequencing and Data
Analysis Services II-62
Helicos BioSciences to Introduce Molecular Diagnostic Tests II-62
Life Technologies to Launch SOLiD™ PI System II-63
Illumina Introduces Range of NGS Kits II-63
Ambry Genetics Introduces Sequence Capture for Roche® and
Illumina® NGS Platforms II-63
New England Biolabs Launches NEBNext® II-63
Ambry Genetics Rolls Out Illumina HiSeq 2000 NGS Services II-63
Integromics Unveils SeqSolve Next Generation Sequencing Software II-64
Agilent Technologies Introduces Agilent SureSelect XT Target
Enrichment System II-64
NuGEN® Technologies Launches Ovation® RNA-Seq FFPE System and
Ovation® WGA FFPE System II-65
NuGEN® Technologies Rolls Out Ovation 3'-DGE System and Encore
NGS Library/Multiplex Systems II-65
454 Life Sciences Introduces GS Junior System II-66
Ambry Genetics Rolls Out Ambry X-Linked Mental Retardation
SuperPANEL™ Genetic Tests Suite II-66
CLC bio Launches Innovative Whole-Genome De Novo Assembler II-66
Life Technologies Introduces 5500 xl SOLiD Sequencer II-67
Ambry Genetics Acquires Illumina BeadXpress and HiSeq 2000
Sequencing System II-67
NanoString Technologies Introduces New Genetic CNV Detection
Solution II-68
Adaptive TCR Introduces New Bioinformatics Software Platform
and Profiling Service II-68
BioBase Biological Databases Unveils New Sequencing Analysis
Solution II-68
Agilent Technologies Launches SureSelect Kinome Target
Enrichment Kit II-69
New England Biolabs Introduces New Range of Reagents II-69
DNAnexus Launches New Web-Based Service for DNA Sequencing Data II-69
Epigentek Group Develops NGS Technology for DNA Bisulfite
Conversion II-69
Genomic Health Develops New Whole Genome Expression Analysis
Method II-69
NuGEN Technologies Introduces Ovation RNA-Seq System II-70
Agilent Technologies Launches SureSelect DNA Capture Array II-70
Rubicon Genomics Launches New PicoPlex Single Cell WGA Kit II-71
LC Sciences Introduces of Custom Target Enrichment Service II-71
CLC bio Introduces CLC Genomics Workbench 3.0 II-71
7. FOCUS ON SELECT GLOBAL PLAYERS II-73
Agilent Technologies, Inc. (US) II-73
Ambry Genetics Corp. (US) II-73
BioNano Genomics, Inc (US) II-73
Caliper Life Sciences, Inc. (US) II-74
Covaris, Inc. (US) II-74
F. Hoffman-La Roche Ltd. (Switzerland) II-74
454 Life Sciences (US) II-75
GenoLogics Life Sciences Software, Inc. (Canada) II-75
Genomic Health, Inc. (US) II-75
Geospiza, Inc. (US) II-76
Helicos BioSciences Corporation (US) II-76
Illumina, Inc. (US) II-76
Ingenuity Systems, Inc. (US) II-76
IntegenX, Inc. (US) II-77
Kapa Biosystems, Inc. (US) II-77
Life Technologies Corporation (US) II-77
Nanostring Technologies, Inc. (US) II-78
New England Biolabs, Inc. (US) II-78
NuGen Technologies, Inc. (US) II-78
RainDance Technologies, Inc. (US) II-79
8. GLOBAL MARKET PERSPECTIVE II-80
Table 4: World Recent Past, Current and Future Analysis for
Next Generation Sequencers by Geographic Region/Country - US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin
America, and Rest of World Markets Independently Analyzed with
Annual Revenue Figures in US$ Million for Years 2009 through
2018 (includes corresponding Graph/Chart) II-80
Table 5: World 10-Year Perspective for Next Generation
Sequencers by Geographic Region/Country - Percentage Breakdown
of Dollar Revenues for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan), Latin America, and Rest of World Markets
for Years 2009, 2012 and 2018 (includes corresponding
Graph/Chart) II-81
III. MARKET
1. THE UNITED STATES III-1
A.Market Analysis III-1
Current and Future Analysis III-1
Key Market Trends III-1
Increasing Use of Sequencing in Complex and Mendelian Diseases III-1
NGS Budgets of American Laboratories to Remain Flat III-1
Competition III-2
Table 6: NGS Sequencing Market in North America (2011):
Percentage Share Breakdown by leading Players -
Illumina/Solexa; Life Technologies, Roche/454 and Helicos
(includes corresponding Graph/Chart) III-2
Table 7: North America Microarray Market in (2011):
Percentage Share Breakdown by leading Players - Illumina
Bead Array, Affymetrix, Agilent Microarray and
Roche/NimbleGen Microarray (includes corresponding
Graph/Chart) III-2
Recent Industry Activity III-3
Product Launches III-23
Select Regional Players III-41
B.Market Analytics III-47
Table 8: US Recent Past, Current and Future Analysis for
Next Generation Sequencers Analyzed with Annual Revenue
Figures in US$ Million for Years 2009 through 2018 (includes
corresponding Graph/Chart) III-47
2. CANADA III-48
A.Market Analysis III-48
Current and Future Analysis III-48
Strategic Corporate Developments III-48
Product Launches III-49
B.Market Analytics III-51
Table 9: Canadian Recent Past, Current and Future Analysis
for Next Generation Sequencers Analyzed with Annual Revenue
Figures in US$ Million for Years 2009 through 2018 (includes
corresponding Graph/Chart) III-51
3. JAPAN III-52
A.Market Analysis III-52
Current and Future Analysis III-52
Recent Industry Activity III-52
B.Market Analytics III-53
Table 10: Japanese Recent Past, Current and Future Analysis
for Next Generation Sequencers Analyzed with Annual Revenue
Figures in US$ Million for Years 2009 through 2018 (includes
corresponding Graph/Chart) III-53
4. EUROPE III-54
A.Market Analysis III-54
Current and Future Analysis III-54
Snapshot of European NGS Market III-54
Market Drivers III-54
Market Constraints III-54
B.Market Analytics III-55
Table 11: European Recent Past, Current and Future Analysis
for Next Generation Sequencers by Country/Region - France,
Germany, Italy, UK, Spain and Rest of Europe Independently
Analyzed with Annual Revenue Figures in US$ Million for
Years 2009 through 2018 (includes corresponding Graph/Chart) III-55
Table 12: European 10-Year Perspective for Next Generation
Sequencers by Country/Region - Percentage Breakdown of
Dollar Sales for France, Germany, Italy, UK, Spain and Rest
of Europe Markets for Years 2009, 2012 and 2018 (includes
corresponding Graph/Chart) III-56
4a. FRANCE III-57
A.Market Analysis III-57
Current and Future Analysis III-57
Strategic Corporate Development III-57
B.Market Analytics III-58
Table 13: French Recent Past, Current and Future Analysis
for Next Generation Sequencers Analyzed with Annual Revenue
Figures in US$ Million for Years 2009 through 2018 (includes
corresponding Graph/Chart) III-58
4b. GERMANY III-59
A.Market Analysis III-59
Current and Future Analysis III-59
Strategic Corporate Developments III-59
Product Launch III-61
B.Market Analytics III-61
Table 14: German Recent Past, Current and Future Analysis
for Next Generation Sequencers Analyzed with Annual Revenue
Figures in US$ Million for Years 2009 through 2018 (includes
corresponding Graph/Chart) III-61
4c. ITALY III-62
Market Analysis III-62
Table 15: Italian Recent Past, Current and Future Analysis
for Next Generation Sequencers Analyzed with Annual Revenue
Figures in US$ Million for Years 2009 through 2018 (includes
corresponding Graph/Chart) III-62
4d. THE UNITED KINGDOM III-63
A.Market Analysis III-63
Current and Future Analysis III-63
Strategic Corporate Developments III-63
Product Launch III-64
B.Market Analytics III-65
Table 16: UK Recent Past, Current and Future Analysis for
Next Generation Sequencers Analyzed with Annual Revenue
Figures in US$ Million for Years 2009 through 2018 (includes
corresponding Graph/Chart) III-65
4e. SPAIN III-66
A.Market Analysis III-66
Current and Future Analysis III-66
Product Launch III-66
B.Market Analytics III-67
Table 17: Spanish Recent Past, Current and Future Analysis
for Next Generation Sequencers Analyzed with Annual Revenue
Figures in US$ Million for Years 2009 through 2018 (includes
corresponding Graph/Chart) III-67
4f. REST OF EUROPE III-68
A.Market Analysis III-68
Current and Future Analysis III-68
Strategic Corporate Developments III-68
Product Launches III-70
F. Hoffman-La Roche Ltd. - A Leading Swiss Player III-71
B.Market Analytics III-72
Table 18: Rest of Europe Recent Past, Current and Future
Analysis for Next Generation Sequencers Analyzed with Annual
Revenue Figures in US$ Million for Years 2009 through 2018
(includes corresponding Graph/Chart) III-72
5. ASIA-PACIFIC III-73
A.Market Analysis III-73
Current and Future Analysis III-73
Select Market Overview III-73
India III-73
Table 19: Indian DNA Sequencers Market (2011): Percentage
Breakdown of Annual Instrument Sales by Segment -
Automated DNA Sequencers, Next Generation Sequencers, and
Manual DNA Sequencers (includes corresponding Graph/Chart) III-73
Major Factors Challenging Growth of Indian NGS Market III-73
Competitive Landscape III-74
China III-74
Strategic Corporate Developments III-74
Product Launch III-78
B.Market Analytics III-79
Table 20: Asia-Pacific Recent Past, Current and Future
Analysis for Next Generation Sequencers Analyzed with Annual
Revenue Figures in US$ Million for Years 2009 through 2018
(includes corresponding Graph/Chart) III-79
6. LATIN AMERICA III-80
Market Analysis III-80
Table 21: Latin American Recent Past, Current and Future
Analysis for Next Generation Sequencers Analyzed with Annual
Revenue Figures in US$ Million for Years 2009 through 2018
(includes corresponding Graph/Chart) III-80
7. REST OF WORLD III-81
Market Analysis III-81
Table 22: Rest of World Recent Past, Current and Future
Analysis for Next Generation Sequencers Analyzed with Annual
Revenue Figures in US$ Million for Years 2009 through 2018
(includes corresponding Graph/Chart) III-81
IV. COMPETITIVE LANDSCAPE
Total Companies Profiled: 83 (including Divisions/Subsidiaries - 93)
The United States (55)
Canada (2)
Japan (3)
Europe (25)
- Germany (7)
- The United Kingdom (4)
- Spain (1)
- Rest of Europe (13)
Asia-Pacific (Excluding Japan) (8)
To order this report:
Genomics Industry: Global Next Generation Sequencers Industry
__________________________
Contact Nicolas: [email protected]
US: (805)-652-2626
Intl: +1 805-652-2626
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