NEW YORK, June 30, 2016 /PRNewswire/ -- Illumina leads the market for Sample Preparation Products for Next-Generation Sequencing, according to Kalorama Information, but there are scores of other providers. The healthcare market research firm said that the market leader of the instruments for next-generation sequencing also leads in the market for sample prep -- products that extract and isolate DNA and perform library management tasks needed for successful sequencing runs, but that competition in sample prep is stiffer than in instruments. The finding was made in Kalorama Information's report: The Market for Sample Preparation in NGS.
With a high level of product introductions, Kalorama said the competition in NGS sample preparation products has increased greatly in the last couple of years. Illumina has been growing its lead both in this segment and the overall sequencer market as its Nextera and TruSeq product lines have been well received by end-users. But it is not alone in the market. Agilent, Thermo Fisher and Fluidigm compete in the space and the number of large firms have made moves towards competing in the market.
"Right now customers are staying with the instrument brand when it comes to sample prep products," said Bruce Carlson, Publisher of Kalorama Information. "Yet the thousands of Illumina installations are a tempting target for suppliers."
The report says there are three other vendors to watch in this segment. Agilent is a contender in second, due to its sustained success in a variety of product areas including target enrichment and library QC. South San Francisco, CA-based Fluidigm has been a leader in the market with its microfluidics technologies including single-cell analysis and library preparation chips. It is a small but established company that has built up a large selection of products over the years. Its Access Array System and Target-Specific Primers have been adopted by many labs for the PCR-based target enrichment prior to NGS.
Qiagen N.V., a global life sciences company based in the Netherlands, has been the dominant supplier of nucleic acid extraction and purification products for some time, along with having many other successful product lines in both research and diagnostics markets. This puts it in a fortunate position, given the need for DNA isolation prior to sequencing and the amazing growth in the NGS market and genomics as a whole in recent years. Qiagen has made many moves in the last couple of years to advance further into the other areas of the sequencing market. In November 2015, Qiagen introduced the GeneReader sequencer, which is sold exclusively as an integrated system along with the QIAcube for DNA extraction, and the QIAcube NGS, which prepares those DNA libraries for sequencing. The company has indicated that it will offer platform-independent versions of its QIAcube sample preparation instruments and software, but that there will also be dedicated versions for the GeneReader that are tightly integrated with the machine. Qiagen has said that it has plans to submit both the sequencer and the Actionable Insights Tumor Panel to the FDA for clearance.
Thermo/ Life Technologies obtained a significant user base through its acquisition of Life Technologies in 2014. The Waltham, MA-based company has experienced respectable adoption of its Ion Torrent systems, but at the same time revenues of its older system, SOLiD, have decreased significantly. Yet Kalorama's report says there have been some recent developments that could improve the situation for Thermo. It has introduced new versions of its Ion Torrent sequencer, the S5 and S5 XL. Thermo has also made several recent deals that could boost its competitiveness in NGS. These include acquisitions such as Affymetrix, Alfa Aesar, and One Lambda, and collaborations including CompanionDx, GlaxoSmithKline, Invivoscribe, Lucigen, Novartis, Pfizer, and Premaitha. For library quality control and size selection, Thermo offers the NanoDrop, Qubit, Quant-IT, and TaqMan Quantitation Kit. The company also offers library preparation products.
There are scores of other companies with sample prep offerings, including Covaris, New England Biolabs, NuGEN, Technologies, PerkinElmer, Roche and RainDance Technologies,
"The entry of companies and interest from established life science players points towards growth in the market," said Carlson.
Kalorama Information's report, The Market for Sample Preparation in NGS contains market sizing and forecast for sample prep, trends, listings of available products and profiles of companies in the market. The report is available from Kalorama Information at: http://www.kaloramainformation.com/Sample-Preparation-Generation-10027181/.
About Kalorama Information
Kalorama Information, a division of MarketResearch.com, supplies the latest in independent medical market research in diagnostics, biotech, pharmaceuticals, medical devices and healthcare; as well as a full range of custom research services. Reports can be purchased through Kalorama's website and are also available on www.marketresearch.com and www.profound.com.
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SOURCE Kalorama Information