FOSTER CITY, California, March 14, 2016 /PRNewswire/ --
MedGenome presented data on its proprietary cancer immunotherapy platform, OncoPept that predicts and prioritizes T-cell neo-epitopes in human and mouse cancers at the Molecular Medicine Tri- Conference 2016, which took place on March 6 - 11, 2016 at San Francisco, CA.
Many pre-clinical and clinical studies have documented the power of T-cell neo epitopes in shaping the immune response to eliminate cancer - the basis for the development of cancer vaccines. MedGenome's OncoPept platform combines exome and RNA-sequencing data and prioritizes the neo-epitopes further with advanced analytics. The platform combines deep sequencing to identify rare variants present in less than 5% of tumor cells to increase the repertoire of mutations that may be targeted by T-cells. The number of mutations is further reduced using multiple prioritization steps to a small list that can be tested as cancer vaccines. In addition, OncoPept seeks to address the challenge faced by the oncology community at large, to discover tumor-intrinsic and extrinsic factors that will increase the patient response to the checkpoint inhibitor drugs significantly over what is achieved to date.
MedGenome is a genomics-driven research and diagnostics company with a mission to improve global health by decoding the genetic information contained in an individual's genome. Our powerful genomics solutions accelerate drug discovery research for pharma and biotech companies. Our unique access to genomics data with clinical and phenotypic data provides insights into complex diseases at the genetic and molecular level to facilitate research in personalized healthcare. MedGenome is the market leader for genetic diagnostic testing in India and has worked with thousands of doctors, hospitals, and patients across India by applying Next Generation Sequencing (NGS) techniques to large disease cohorts in cancer, eye and neurological disorders, diabetes, cardiovascular diseases and rare cancers. For more information, visit us at http://www.medgenome.com
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