MediPoint: Knee Replacement - APAC Analysis and Market Forecasts

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MediPoint: Knee Replacement - APAC Analysis and Market Forecasts
http://www.reportlinker.com/p01936456/MediPoint-Knee-Replacement---APAC-Analysis-and-Market-Forecasts.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Orthopedic

MediPoint: Knee Replacement - APAC Analysis and Market Forecasts

Summary

The current knee replacement market is a crowded space, with an increasing number of companies offering a myriad of partial, primary/total, and revision prostheses to meet orthopedic surgeons' demands in the management of knee diseases, primarily osteoarthritis. Worldwide, the primary/total knee segment represents about 80–90% of the entire knee market, with the remainder being partial knee and revision knee. Overall, clinical data show that short- to medium-term survivorship is excellent after almost all common types of knee replacement, regardless of fixation, constraint, and bearing type. Future competition among vendors will be more likely to center on the instrumentation and the ancillary equipment, such as patient-specific instruments, navigation systems, and robotic systems.

In contrast to the general picture in developed countries, the APAC countries are relative laggards in the utilization of knee replacement, primarily due to the slow rate of adoption of a westernized lifestyle and OA development in their populations. Japan is comparable to the 5EU and US from the perspective of product adoption and the utilization of healthcare services, yet the knee replacement procedure volume in Japan is expected to increase at a slower pace than in India and China.

Scope

- An overview of hypertension, which includes epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines.
- Annualized APAC Knee replacement market revenue and future forecasts from 2009 to 2011, forecast for 7 years to 2018.
- Investigation of current and future market competition for Knee replacement
- Insightful review of the key industry drivers, restraints and challenges as well as predicted impact of key events.
- Competitor assessment including device approval analysis and device sales forecasts.
- Marketed and pipeline product profiles covering efficiency, safety, clinical study details, device approvals, product positioning and device sales forecast.
- Analysis of unmet needs within the market and opportunities for future players.
- Technology trends evaluation to assess strength of pipeline.
- An overview of all devices in development including clinical study details, design and material selection considerations, efficacy reports, and device approval timelines.
- Company profiles including business description, financial overview and SWOT analysis.
- Coverage of key market players.
- Strategic assessment of the Knee replacement sector through market impact analysis, future market scenario and company analysis.
- Direct quotes from Key Opinion Leaders (KOL) as well as cardiologists

Reasons to buy

- Understand the trends shaping and driving APAC Knee replacement market.
- Realize device preferences of physicians who have performed the tests already.
- Access market sizing, forecasts and quantified growth opportunities in APAC Knee replacement market through 2018.
- Quantify candidate patient populations to better design product pricing & launch plans.
- Drive revenues, formulate effective sales and marketing strategies and gain in-depth understanding of the competitive landscape.
- Perform benchmarking analysis of growth opportunities against currently marketed products.
- Assess competitiveness of products in market by understanding the strengths and weaknesses of current competition.
- Take a comprehensive look at the market's device pipeline and identify promising, paradigm-shifting products.
- Create an effective counter-strategy to gain a competitive advantage against those currently in the market.
- Organize your sales and marketing efforts by identifying the market categories and segments that present the best opportunities for growth.
- What's the next big thing in APAC Knee replacement market landscape? Identify, understand and capitalize.
1 Table of Contents
1 Table of Contents 7
1.1 List of Tables 13
1.2 List of Figures 18
2 Introduction 21
2.1 Catalyst 22
2.2 Related Reports 22
3 Disease Overview 23
3.1 Anatomy and Physiology 23
3.2 Pathophysiology 25
3.2.1 Overview 25
3.2.2 Primary Osteoarthritis 25
3.2.3 Rheumatoid Arthritis 26
3.2.4 Post-Traumatic Arthritis 27
3.2.5 Avascular Necrosis 27
3.3 Clinical Presentation 28
3.3.1 Diagnosis 28
3.4 Clinical Outcomes 29
3.4.1 Overview 29
3.4.2 Conservative Treatments 29
3.4.3 Joint-Preserving Treatments 31
3.4.4 Joint Replacement 33
3.5 Economic Impact 44
3.5.1 Asia-Pacific 45

4 Industry Overview 46
4.1 Procedural Trends 46
4.1.1 Asia-Pacific 46
4.2 Market Access 50
4.2.1 Asia-Pacific 50
4.3 Regulatory Issues/Recalls 59
4.3.1 DePuy Orthopaedic's Diaphyseal Sleeve Components of the Limb Preservation System (LPS) 59
4.3.2 Stryker's ShapeMatch Cutting Guides 59
4.3.3 B. Braun's Columbus Total Knee System's Cementless Version 60
4.3.4 Smith & Nephew's Journey Uni Tibial Insert, Right Medial/Left Lateral 60
4.4 Mergers and Acquisitions/Key Partnerships 61
4.4.1 Stryker's Acquisition of MAKO Surgical 61
4.4.2 MicroPort Medical B.V.'s Acquisition of Wright Medical's OrthoRecon Business 61
4.4.3 Stryker's Extension of Co-Marketing Agreement with OrthoSensor 62
4.4.4 Blue Belt Technologies' Co-Marketing Agreement with DJO Surgical 62
4.4.5 Biomet and OrthoSensor Enter Into Co-Promotion Partnership 62
4.4.6 Italian Consortium 2IL Orthopaedics Acquires Corin Group 63
4.4.7 Smith & Nephew Acquires LifeModeler, Inc. (LMI) 63
4.5 Market Drivers, Opportunities, and Barriers 64
4.5.1 Market Drivers 64
4.5.2 Market Opportunities 69
4.5.3 Market Barriers 75
5 Competitive Assessment 80
5.1 Overview 80
5.2 Global Market Share 82
5.3 B. Braun 83
5.3.1 Primary Knee Replacement 83
5.3.2 Partial Knee Replacement 85
5.3.3 Revision Knee Replacement 86
5.3.4 SWOT Analysis 86
5.4 Biomet 87
5.4.1 Primary Knee Replacement 87

5.4.2 Partial Knee Replacement 90
5.4.3 Revision Knee Replacement 91
5.4.4 SWOT Analysis 92
5.5 DePuy Synthes 93
5.5.1 Primary Knee Replacement 93
5.5.2 Partial Knee Replacement 98
5.5.3 Revision Knee Replacement 99
5.5.4 SWOT Analysis 100
5.6 DJO Surgical 101
5.6.1 Primary Knee Replacement 101
5.6.2 Partial Knee Replacement 104
5.6.3 Revision Knee Replacement 104
5.6.4 SWOT Analysis 105
5.7 Exactech 106
5.7.1 Primary Knee Replacement 106
5.7.2 Partial Knee Replacement 107
5.7.3 Revision Knee Replacement 108
5.7.4 SWOT Analysis 108
5.8 Smith & Nephew 109
5.8.1 Primary Knee Replacement 109
5.8.2 Partial Knee Replacement 113
5.8.3 Revision Knee Replacement 114
5.8.4 SWOT Analysis 115
5.9 Stryker 116
5.9.1 Primary Knee Replacement 116
5.9.2 Partial Knee Replacement 119
5.9.3 Revision Knee Replacement 120
5.9.4 SWOT Analysis 121
5.10 Wright Medical (MicroPort) 122
5.10.1 Primary Knee Replacement 122
5.10.2 Revision Knee Replacement 124
5.10.3 SWOT Analysis 125
5.11 Zimmer 126
5.11.1 Primary Knee Replacement 126
5.11.2 Partial Knee Replacement 132
5.11.3 Revision Knee Replacement 132

5.11.4 SWOT Analysis 134
6 Unmet Needs 135
6.1 Availability of Long-Term Clinical Data 135
6.2 Complete Knee Platform 137
6.3 Need for Cost-Containment 139
6.4 Training for Computer Navigation Technologies 140
6.5 Continued Innovations in Instrumentation 142
6.6 Advanced Materials 143
6.7 Implants for Metal-Sensitive Patients 144
6.8 National Joint Registry 145
7 Pipeline Products 147
7.1 Overview 147
7.2 Biomet's Vanguard XP Total Knee System 147
7.3 Corentec's Lospa Total Knee System 148
7.4 NovoSource's NovoKnee 148
7.5 Pipeline Orthopedics' NEO PS Knee System 148
7.6 Bonovo Orthopedics' JMM Total Knee System 148
7.7 Corin Group's Unity Knee Systems 149
7.8 Kinamed's GEM Total Knee System 149
7.9 Emerge Medical 149
8 Current and Future Players 150
8.1 Trends in Corporate Strategy 150
8.2 Established Players 151
8.2.1 B. Braun 151
8.2.2 Biomet 154
8.2.3 Corin Group 158
8.2.4 DePuy Synthes 160
8.2.5 DJO Global 164
8.2.6 Exactech 167
8.2.7 Lima Corporate 170
8.2.8 Medacta 172
8.2.9 Smith & Nephew 174
8.2.10 Stryker 178
8.2.11 Waldemar LINK 181
8.2.12 Wright Medical Group (MicroPort) 183

8.2.13 Zimmer Holdings 186
8.2.14 Other Established Players 191
8.3 Emerging Players 192
8.3.1 Blue Belt Technologies 192
8.3.2 ConforMIS 194
8.3.3 MAKO Surgical 197
8.3.4 OmniLife science 199
8.3.5 Other Emerging Players 202
9 Market Outlooks 203
9.1 Japan 203
9.2 China 206
9.3 India 209
10 Appendix 212
10.1 Abbreviations 212
10.2 Bibliography 215
10.3 Report Methodology 235
10.3.1 Overview 235
10.3.2 Coverage 235
10.3.3 Secondary Research 236
10.3.4 Forecasting Methodology 237
10.3.5 Primary Research - Key Opinion Leader Interviews 238
10.3.6 Expert Panel Validation 238
10.4 Physicians and Specialists Included in This Study 239
10.5 Physician Survey 241
10.6 About the Authors 242
10.6.1 Analysts 242
10.6.2 Bonnie Bain, Ph.D., Global Head of Healthcare 243
10.7 About MediPoint 244

10.8 About GlobalData 244
10.9 Disclaimer 244

1.1 List of Tables

Table 1: Risk Factors for Primary OA of the Knee 26
Table 2: Common Clinical Symptoms of Knee Arthritis 28
Table 3: Common Reasons for Failed Knee Implants 40
Table 4: Advantages of CAS 42
Table 5: Direct, Indirect, and Intangible Costs of Arthritis 44
Table 6: Common Reasons for Revision After Total and Partial Knee Replacement 76
Table 7: Product Profile - Columbus Total Knee System 84
Table 8: Product Profile - e.motion Total Knee System 85
Table 9: Product Profile - univation Unicondylar Knee System 85
Table 10: Product Profile - B. Braun's Revision Knee Replacement Systems 86
Table 11: SWOT Analysis - B. Braun's Knee Portfolio 86
Table 12: Product Profile - Vanguard Complete Knee System 88
Table 13: List of Select Clinical Studies - Vanguard Complete Knee System 88
Table 14: Product Profile - AGC Total Knee System 89
Table 15: List of Select Clinical Studies - AGC Total Knee System 90
Table 16: Product Profile - Biomet's Partial Knee Replacement Systems 91
Table 17: Product Profile - Biomet's Revision Knee Replacement Systems 91
Table 18: Select Clinical Study - Biomet's Revision Knee Replacement Systems 92
Table 19: SWOT Analysis - Biomet's Knee Portfolio 92
Table 20: Product Profile - LCS Complete Knee Systems 94
Table 21: List of Select Clinical Studies - LCS Complete Knee System 94
Table 22: Product Profile - Sigma Knee System 96
Table 23: List of Select Clinical Studies - Sigma Knee System 96
Table 24: Product Profile - Attune Knee System 97
Table 25: List of Select Clinical Studies - Attune Knee System 98
Table 26: Product Profile - Sigma HP Partial Knee System 98
Table 27: Product Profile - DePuy's Revision Knee Replacement Systems 99
Table 28: List of Select Clinical Studies - DePuy's Revision Knee Replacement Systems 100
Table 29: SWOT Analysis - DePuy's Knee Portfolio 100
Table 30: Product Profile - Movation Knee System 101
Table 31: Product Profile - 3D Knee System 102
Table 32: Product Profile - Foundation Knee System 103
Table 33: Product Profile - EPIK Knee System 104
Table 34: Product Profile - Foundation Revision Knee System 104

Table 35: SWOT Analysis - DJO's Knee Portfolio 105
Table 36: Product Profile - Optetrak Knee System 107
Table 37: Product Profile - Optetrak Unicondylar Knee System 107
Table 38: Product Profile - Optetrack Constrained Condylar (CC) Knee System 108
Table 39: SWOT Analysis - Exactech's Knee Portfolio 108
Table 40: Product Profile - LEGION Knee System 110
Table 41: List of Select Clinical Studies - GENESIS II Total Knee System 110
Table 42: Product Profile - JOURNEY Knee System 112
Table 43: List of Select Clinical Studies - JOURNEY Knee System 112
Table 44: Product Profile - Smith & Nephew's Partial Knee Replacement Systems 113
Table 45: Product Profile - Smith & Nephew's Revision Knee Systems 114
Table 46: SWOT Analysis - Smith & Nephew's Knee Portfolio 115
Table 47: Product Profile - Triathlon Total Knee System 117
Table 48: List of Select Clinical Studies - Triathlon Total Knee System 117
Table 49: Product Profile - Scorpio Knee System 118
Table 50: Product Profile - Stryker's Partial Knee Replacement Systems 119
Table 51: Product Profile - Stryker's Revision Knee Replacement Systems 120
Table 52: Select Clinical Study - Stryker's Revision Knee Replacement System 120
Table 53: SWOT Analysis - Stryker's Knee Portfolio 121
Table 54: Product Profile - Advance Knee System 123
Table 55: Product Profile - Evolution Medial-Pivot Knee System 124
Table 56: Product Profile - Wright Medical's Revision Knee Replacement Systems 124
Table 57: SWOT Analysis - Wright Medical's Knee Portfolio 125
Table 58: Product Profile - NexGen Knee System 127
Table 59: List of Select Clinical Studies - NexGen Knee System 128
Table 60: Product Profile - Gender Solutions Knee Systems 129
Table 61: List of Select Clinical Studies - Gender Solutions Knee System 130
Table 62: Product Profile - Persona Knee System 131
Table 63: List of Select Clinical Studies - Persona Knee System 131
Table 64: Product Profile - Zimmer's Partial Knee Replacement Systems 132
Table 65: Product Profile - Zimmer's Revision Knee Replacement Systems 133
Table 66: SWOT Analysis - Zimmer's Knee Portfolio 134
Table 67: Pipeline Products in the Global Knee Replacement Market, 2013 147
Table 68: Company Profile - B. Braun 152
Table 69: Portfolio Assessment - B. Braun 153
Table 70: SWOT Analysis - B. Braun 153

Table 71: Company Profile - Biomet 155
Table 72: Portfolio Assessment - Biomet 156
Table 73: SWOT Analysis - Biomet 157
Table 74: Company Profile - Corin Group 158
Table 75: Portfolio Assessment - Corin Group 159
Table 76: SWOT Analysis - Corin Group 160
Table 77: Company Profile - DePuy Synthes 161
Table 78: Portfolio Assessment - DePuy Synthes 162
Table 79: SWOT Analysis - DePuy Synthes 163
Table 80: Company Profile - DJO Global 164
Table 81: Portfolio Assessment - DJO Global 165
Table 82: SWOT Analysis - DJO Global 166
Table 83: Company Profile - Exactech 167
Table 84: Portfolio Assessment - Exactech 168
Table 85: SWOT Analysis - Exactech 169
Table 86: Company Profile - Lima Corporate 170
Table 87: Portfolio Assessment - Lima Corporate 171
Table 88: SWOT Analysis - Lima Corporate 171
Table 89: Company Profile - Medacta 172
Table 90: Portfolio Assessment - Medacta 173
Table 91: SWOT Analysis - Medacta 173
Table 92: Company Profile - Smith & Nephew 175
Table 93: Portfolio Assessment - Smith & Nephew 176
Table 94: SWOT Analysis - Smith & Nephew 177
Table 95: Company Profile - Stryker 179
Table 96: Portfolio Assessment - Stryker 180
Table 97: SWOT Analysis - Stryker 181
Table 98: Company Profile - Waldemar LINK 182

Table 99: Portfolio Assessment - Waldemar LINK 182
Table 100: SWOT Analysis - Waldemar LINK 183
Table 101: Company Profile - Wright Medical Group 184
Table 102: Portfolio Assessment - Wright Medical Group 185
Table 103: SWOT Analysis - Wright Medical Group 186
Table 104: Company Profile - Zimmer Holdings 187
Table 105: Portfolio Assessment - Zimmer Holdings 189
Table 106: SWOT Analysis - Zimmer Holdings 190
Table 107: Other Established Players in the Global Knee Replacement Market, 2013 191
Table 108: Company Profile - Blue Belt Technologies 192
Table 109: Portfolio Assessment - Blue Belt Technologies 193
Table 110: SWOT Analysis - Blue Belt Technologies 194
Table 111: Company Profile - ConforMIS 195
Table 112: Portfolio Assessment - ConforMIS 196
Table 113: SWOT Analysis - ConforMIS 196
Table 114: Company Profile - MAKO Surgical 197
Table 115: Portfolio Assessment - MAKO Surgical 198
Table 116: SWOT Analysis - MAKO Surgical 199
Table 117: Company Profile - OMNIlife science 200
Table 118: Portfolio Assessment - OMNIlife science 201
Table 119: SWOT Analysis - OMNIlife science 201
Table 120: Other Emerging Players in the Global Knee Replacement Market, 2013 202
Table 121: Japan Knee Replacement Market Sales Forecast ($m), 2010-2019 203
Table 122: China Knee Replacement Market Sales Forecast ($m), 2010-2019 206
Table 123: India Knee Replacement Market Sales Forecast ($m), 2010-2019 209
Table 124: Abbreviations 212
Table 125: Physicians Surveyed, By Country 241

1.2 List of Figures
Figure 1: Schematic Diagram of Knee Anatomy 23
Figure 2: Unicompartmental Knee Replacement 34
Figure 3: Patellofemoral Knee Replacement 36
Figure 4: Bicompartmental Knee Replacement 37
Figure 5: CR and PS Designs 38
Figure 6: Knee Replacement Procedure Volume, APAC, 2010-2019 46
Figure 7: Partial Knee Replacement Procedure Volume, APAC, 2010-2019 47
Figure 8: Primary Knee Replacement Procedure Volume, APAC, 2010-2019 48
Figure 9: Revision Knee Replacement Procedure Volume, APAC, 2010-2019 49
Figure 10: Adoption Trend for Total Knee Implants in APAC, Fixed-Bearing vs. Mobile-Bearing, 2011-2015 51
Figure 11: Adoption Trend for Total Knee Implants in APAC, Cruciate-Retaining vs. Cruciate-Sacrificing, 2011-2015 52
Figure 12: Adoption Trend for Revision Knee Implants in APAC, 2011-2015 53
Figure 13: Adoption Trend for Computer-Assisted Technologies in APAC, 2012 55
Figure 14: Global Knee Replacement Market, Competitive Landscape by Sales Revenue, 2012 82
Figure 15: Columbus Total Knee System 83
Figure 16: e.motion Total Knee System 84
Figure 17: Vanguard Complete Knee System 87
Figure 18: AGC Total Knee System 89
Figure 19: LCS Complete Knee System 93
Figure 20: Sigma Knee System 95
Figure 21: Attune Knee System 97
Figure 22: Movation Knee System 101
Figure 23: 3D Knee System 102
Figure 24: Foundation Knee System 103
Figure 25: Optetrak Logic Knee System 106
Figure 26: GENESIS II Total Knee System 109

Figure 27: Journey Knee System 111
Figure 28: Triathlon Total Knee System 116
Figure 29: Scorpio Knee System 118
Figure 30: Advance Knee System 122
Figure 31: Evolution Medial-Pivot Knee System 123
Figure 32: NexGen Knee System 126
Figure 33: Gender Solutions' NexGen High-Flex Knee 129
Figure 34: Persona Knee System 131
Figure 35: Level of Impact of the Availability of Long-Term Clinical Data Upon Decision-Making (n=103) 136
Figure 36: Level of Impact of a Complete Knee System Upon Decision-Making (n=103) 137
Figure 37: Japan Knee Replacement Market Sales Forecast ($m), 2010-2019 204
Figure 38: Japan Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 205
Figure 39: China Knee Replacement Market Sales Forecast, 2010-2019 207
Figure 40: China Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 208
Figure 41: India Knee Replacement Market Sales Forecast ($m), 2010-2019 210
Figure 42: India Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 211

Companies Mentioned

B. Braun
Biomet
DePuy Synthes
DJO Surgical
Exactech
Smith & Nephew
Stryker
Wright Medical (MicroPort)
Zimmer


To order this report: MediPoint: Knee Replacement - APAC Analysis and Market Forecasts
http://www.reportlinker.com/p01936456/MediPoint-Knee-Replacement---APAC-Analysis-and-Market-Forecasts.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Orthopedic

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