New England Biolabs® and Benchling Collaborate to Simplify Golden Gate Assemblies

IPSWICH, Mass. and SAN FRANCISCO, March 20, 2015 /PRNewswire/ -- New England Biolabs, Inc. (NEB®) and Benchling, Inc., today announced a collaboration to simplify the design of cloning experiments that utilize Golden Gate Assembly. Together, the companies are launching a free online tool that will be available both as a part of Benchling's Molecular Biology app and as the NEB Golden Gate Assembly Tool from New England Biolabs at GoldenGate.neb.com.

"We wanted to develop a tool that helps not just biologists currently working with the Golden Gate Assembly method, but also those who are using conventional cloning methods and looking to make the leap to a more powerful system," said Sajith Wickramasekara, co-founder and CEO of Benchling. "This is a great example of how Benchling tools can make science more efficient by replacing archaic lab tools and protocols with robust, modern technology."

"By working with Benchling, we have been able to introduce a tool that will dramatically simplify experimental design for our customers, allowing them to optimize the conditions required for successful Golden Gate Assembly," said Isaac Meek, Business Development Manager at NEB.  "We have been very impressed with the Benchling team and pleased by their ability to quickly develop an advanced solution that will benefit our customers."

Advances in cloning technologies have focused on the assembly of multiple DNA fragments, which can be made more efficient with techniques such as Golden Gate. Golden Gate is a method that utilizes Type IIS restriction enzymes to allow scientists to assemble up to nine DNA fragments in a single step.

The assembly tool designs the Golden Gate reaction for the user, minimizing the risk of incorrectly designed primers and overlaps. Scientists input the DNA fragments they would like to combine and the tool simulates the reaction, designs the primers and generates the final construct. Users can then adjust the design, export the results and download a protocol.

To access the NEB Golden Gate Assembly Tool please visit GoldenGate.neb.com. More information on products available for Golden Gate Assembly from NEB can be found at www.neb.com/E1600.

About New England Biolabs
Established in the mid 1970's, New England Biolabs, Inc. (NEB) is the industry leader in the discovery and production of enzymes for molecular biology applications and now offers the largest selection of recombinant and native enzymes for genomic research. NEB continues to expand its product offerings into areas related to PCR, gene expression, sample preparation for next generation sequencing, synthetic biology, glycobiology, epigenetics and RNA analysis. Additionally, NEB is focused on strengthening alliances that enable new technologies to reach key market sectors, including molecular diagnostics development. New England Biolabs is a privately held company, headquartered in Ipswich, MA, and has extensive worldwide distribution through a network of exclusive distributors, agents and seven subsidiaries located in Canada, China, France, Germany, Japan, Singapore and the UK. For more information about New England Biolabs visit www.neb.com.

NEB® and NEW ENGLAND BIOLABS® are registered trademarks of New England Biolabs, Inc.

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SOURCE New England Biolabs

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