BOSTON, March 23, 2017 /PRNewswire/ -- Despite the prevalence of muscle cramps, these debilitating and sometimes competition-ending occurrences are poorly understood and can be crippling for athletes at any level. Millions of athletes and fitness enthusiasts suffer from painful, unpredictable and game-stopping muscle cramps that affect strength and physical abilities despite proper training, nutrition and hydration. Common, unproven theories on the cause of muscle cramps include dehydration and electrolyte imbalance, but a newly-published study in the journal of Muscle & Nerve features breakthrough research that muscle cramps originate from hyper-excited motor neurons and can be addressed by using HOTSHOT®, a spicy 1.7-ounce sports shot.
Muscle & Nerve is a reputable, international and interdisciplinary publication focusing on the latest scientific studies concerning the muscle, neuromuscular junction and the central nervous system. The study, conducted by researchers at the esteemed Noll Laboratory at Penn State University, shows that targeting transient receptor potential (TRP) channels through activators contained in HOTSHOT stops muscle cramps where they start: at the nerve. The published findings from Penn State indicate that taking HOTSHOT decreased the duration and intensity of cramps in this carefully controlled experiment. In addition, when cramps did occur, study participants reported decreased muscle soreness immediately after the cramp ended.
"The study that we undertook at Penn State was a randomized, placebo-controlled, double-blind study, and I think that athletes appreciate the solid science that demonstrates HOTSHOT's ability to control muscle cramps. HOTSHOT was significantly more effective at mitigating muscle cramps than a control beverage without the active ingredients," said W. Larry Kenney, Ph.D., FASCM, Marie Underhill Noll Chair in Human Performance and Professor of Physiology and Kinesiology at Penn State University. "While HOTSHOT was effective at mitigating the magnitude of muscle cramps, it did not affect any of the fine motor skills inherent in many sports. The findings suggest that HOTSHOT can level the playing field for many athletes who regularly experience muscle cramps."
Muscle cramps can be the difference between victory over an opponent or achieving a personal best in an event or competition. What sets HOTSHOT apart from other products is the depth of the science supporting it.
"Our scientific insight led to the discovery that sensory neurons affecting muscle function can be stimulated via TRP ion channels in order to prevent and treat muscle cramps," said Nobel Prize-winning neuroscientist/endurance athlete Rod MacKinnon, MD & co-inventor of HOTSHOT. "We have scientifically proven the efficacy of HOTSHOT on muscle cramps and are exploring HOTSHOT's additional potential benefits on Neuro Muscular Performance in collaboration with other academic institutions."
Invented by MacKinnon, in collaboration with Harvard Medical School neurobiology professor, Bruce Bean, HOTSHOT is comprised of a proprietary formula of GMO-free organic ingredients with a spicy kick. HOTSHOT is also NSF Certified for Sport® as well as vegan and gluten-free. Consumed before, during or after exercise, HOTSHOT facilitates the synchronization of communication between the nerves and muscles thereby boosting an athlete's Neuro Muscular Performance (NMP) to prevent and treat muscle cramps.
Many existing "remedies" that target the muscle have limited scientific evidence that they work. HOTSHOT is a brand new concept in sports nutrition. It works by stimulating sensory nerves to affect muscle function. No other consumer product has demonstrated significant efficacy in mitigating muscle cramps. The proprietary HOTSHOT formulation has been extensively tested in clinical settings, as well as by amateur and world-class athletes across endurance sports, track and field, professional football and tennis.
HOTSHOT is available online at www.TeamHOTSHOT.com, on Amazon.com and at select specialty retailers in California, Colorado, Illinois, Massachusetts and Texas. A single serve bottle is $7 USD, while 6-bottle and 12-bottle packs are $35 and $65 USD, respectively.
Invented by Rod MacKinnon, a Nobel Prize-winning neuroscientist and endurance athlete, in collaboration with a Harvard Medical School neurobiology professor Bruce Bean, HOTSHOT® is the sports shot with a kick that is scientifically proven to prevent and treat muscle cramps. A scientific breakthrough in sports nutrition, HOTSHOT is a kick-ass proprietary formulation of organic ingredients that boosts Neuro Muscular Performance – how an athlete's nerves and muscles work together in an optimal way. MacKinnon and Bean spent several years calibrating this precise formulation of Transient Receptor Potential (TRP) activator ingredients that stimulate TRP ion channels in the mouth, esophagus and stomach that directly influence and regulate nerve function. Translation? HOTSHOT stops muscle cramps where they start – at the nerve – allowing athletes to push harder, train longer and finish stronger. HOTSHOT is a USDA Certified Organic product that is non-GMO Project Verified and NSF Certified for Sport®, as well as vegan and gluten-free. To learn more, visit www.TeamHOTSHOT.com. HOTSHOT is a product of Flex Innovation Group LLC, a division of Flex Pharma, Inc. (Nasdaq FLKS).
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