OncoSec Initiates Phase II Clinical Program in Cutaneous T-Cell Lymphoma and Doses First Patient Study Marks First Time Immunotherapy Delivered with Electroporation Will Be Evaluated for This Condition
Dr. Ai said, "There exists a substantial need for novel treatments for cutaneous T-cell lymphoma. The role of electroporation in enhancing the efficiency and/or the tolerability of various agents, such as DNA IL-12, can be delivered to patients is well worth studying."
About Cutaneous T-Cell Lymphoma
Cutaneous T-cell lymphoma (CTCL) is a heterogeneous class of non-Hodgkin's lymphoma, which is a type of cancer of the immune system, with the most common forms being mycosis fungoides (MF) and Sezary syndrome (SS). The malignant T cells in the body initially migrate to the skin, causing various lesions to appear. These lesions change the depth of skin penetration as the disease progresses, typically beginning as what appears to be a rash, which can be very itchy and eventually forming plaque tumors as well as spreading to other parts of the body other than skin. The incidence of CTCL in the United States is approximately 1,500 new cases per year.
About OncoSec Medical Inc.
OncoSec Medical Inc. is a biopharmaceutical company developing advanced-stage OMS ElectroOncology therapies to treat solid tumors and metastatic disease. OMS ElectroOncology therapies address an unmet medical need and represent a potential solution for less invasive and less expensive therapies that are able to minimize the detrimental effects resulting from traditional cancer treatments. OncoSec's core technology is based upon its proprietary use of an electroporation platform, to dramatically enhance the delivery and uptake of a locally delivered DNA-based immuno-cytokine or a chemotherapeutic agent. Treatment of various solid cancers using these targeted anti-cancer agents has demonstrated selective destruction of cancerous cells while sparing healthy normal tissues during early and late stage clinical trials. OncoSec's clinical programs include three Phase II clinical trials for OMS ElectroImmunotherapy targeting lethal skin cancers. More information is available at www.oncosec.com.
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