SCOTTSDALE, Ariz., Dec. 24, 2015 /PRNewswire/ -- Carolann Tutera president of SottoPelle® attended the premiere of the movie Concussion in Scottsdale, Arizona along with NFL Football Legend and SottoPelle patient Jim McMahon. Both felt it was important to attend the movie premiere and help raise awareness to the serious issue of Traumatic Brain Injury (TBI).
Football players and other athletes are being hit so hard that concussions are occurring at a higher rate now than in the past. According to the statistics on Frontline.org called "Concussion Watch:"
The number of players with concussions listed on injury reports is on pace to increase more than 9 percent from last year, to an average of nearly 9 per week. The NFL averaged 5.4 per week in 2009, 7.6 in 2010, and 8.4 last year. 
These numbers only represent those being reported as "concussions" in the NFL, and dependent on other reporting variables. Many sustain long term damage to their brain from game related activities. Players can experience repeated concussions in the course of their careers as in the case of NFL quarterback Jim McMahon, Hall of Famers Paul Krause, Joe DeLamielleure and countless others. When this happens the brain doesn't function normally. The movie centers on the accomplished pathologist Dr. Bennet Omalu who uncovers the truth about brain damage in football players who suffer repeated concussions in the course of normal play. The movie Concussion again raises awareness into this issue and the implications of all involved in the consequences of CTE (chronic traumatic encephalopathy) for athletes. It is important to remember, that concussions are also prevalent in our veterans who are similarly injured in the course of their service to our country.
SottoPelle® has been actively treating those with TBI for years. Life Extension  discussed the link between traumatic brain injury and hormone deficiency last year. Studies show the critical role of hormones in traumatic brain injury and disease.
Many studies demonstrate that hypopituitarism—a condition in which the pituitary fails to produce normal hormone levels—is relatively common following TBI,  affecting at least 50 to 76% of victims. [30-32] Sometimes hypopituitarism diagnoses are not made for more than 20 years after the injury. 
Brain-injured patients who have a deficiency in growth hormone exhibit greater deficits in attention, executive functioning, memory, and emotion than patients with normal growth hormone levels.  Growth hormone binds to receptors found in the brain, especially in regions responsible for learning and memory. [35,36]
The late founder of SottoPelle® Dr. Gino Tutera dedicated his life to helping others and was very focused on the use of BHRT on TBI in the last twenty years. His efforts are realized by the benefits voiced by NFL players like Jim McMahon, Paul Krause, Bobby Bell and many others who are experiencing an improved quality of life and relief of some of their symptoms. Recent media and now the movie Concussion have again highlighted the prevalence and damage of TBI suffered by athletes over the decades. The movie also seems to emphasize the resistance of many to acknowledge the scope of the problem,
SottoPelle® is committed to helping NFL players, veterans, and anyone else with TBI to improve their quality of life. SottoPelle recognizes and understand that TBI can cause devastating quality of life issues for many are dedicated to expanding their reach and efforts to minimize the cognitive and physical effects that standard therapies cannot fully alleviate in many patients.
SottoPelle® is an international leader in Bio-Identical Hormone Therapy headquartered in Scottsdale, Ariz. The company is also creator of BioCalc®, a pellet-dosing tool that has a patent pending to SottoPelle® for more information on SottoPelle® visit: www.SottoPelletherapy.com
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 Hohl A, Mazzuco TL, Coral MH, Schwarzbold M, Walz R. Hypogonadism after traumatic brain injury. Arq Bras Endocrinol Metabol. 2009 Nov;53(8):908-14.
 Klose M, Juul A, Struck J, Morgenthaler NG, Kosteljanetz M, Feldt-Rasmussen U. Acute and long-term pituitary insufficiency in traumatic brain injury: a prospective single-centre study. Clin Endocrinol (Oxf). 2007 Oct;67(4):598-606.
 Agha A, Rogers B, Mylotte D, et al. Neuroendocrine dysfunction in the acute phase of traumatic brain injury. Clin Endocrinol (Oxf). 2004 May;60(5):584-91.
 Agha A, Rogers B, Sherlock M, et al. Anterior pituitary dysfunction in survivors of traumatic brain injury. J Clin Endocrinol Metab. 2004 Oct;89(10):4929-36.
 Aimaretti G, Ghigo E. Traumatic brain injury and hypopituitarism. ScientificWorldJournal. 2005 Sep 15;5:777-81.
 Leon-Carrion J, Leal-Cerro A, Cabezas FM, et al. Cognitive deterioration due to GH deficiency in patients with traumatic brain injury: a preliminary report. Brain Inj. 2007 Jul;21(8):871-5.
 Van Dam PS, Aleman A, de Vries WR, et al. Growth hormone, insulin-like growth factor I and cognitive function in adults. Growth Horm IGF Res. 2000 Apr;10 Suppl B:S69-73.
 Creyghton WM, van Dam PS, Koppeschaar HP. The role of the somatotropic system in cognition and other cerebral functions. Semin Vasc Med. 2004 May;4(2):167-72.
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