PR Newswire: news distribution, targeting and monitoring
2014

When One Plus One Equals Three

Share with Twitter Share with LinkedIn

SANTA ROSA, Calif., May 24, 2012 /PRNewswire/ --  In a groundbreaking study, Modified Citrus Pectin (MCP), a highly researched natural compound enhanced the anti-cancer effects of two poly-botanical formulas. When co-administered with formulas that attack breast and prostate cancer, MCP significantly increased their anti-cancer action, further reducing metastasis in highly invasive breast and prostate cancer cells. The study was led by researchers at the Cancer Research Laboratory at Indiana University Health and Indiana University School of Medicine, and published in the peer review journal Integrative Cancer Therapies.

"We asked a simple question of whether one plus one can equal more than two," said lead investigator Dr. Daniel Sliva, associate professor at the Indiana University School of Medicine. "We know that certain molecules in cancer cells are responsible for their aggressive behavior.
The synergistic effects seen in this study show that we can further suppress these molecules and significantly reduce the cancer cells' aggressiveness."

In the study, low concentrations of the anti-breast cancer formula decreased breast cancer cell adhesion to human fibronectin by 21 percent. However, when co-administered with Modified Citrus Pectin, researchers observed a 40 percent decrease.

In addition, the anti-prostate cancer formula, administered alone, decreased prostate cancer cell adhesion by 9 percent. When MCP was added, adhesion was suppressed by up to 40 percent.

The study also showed that cancer cell migration was also reduced by combining MCP with the prostate and breast formulas.

"This new study is particularly important because it demonstrates that when MCP is combined with either the prostate or breast formula, lower dosages provided more powerful synergistic anti-cancer effects than were observed when these supplements were studied on their own," said
co-author and formulator, Dr. Isaac Eliaz.

It is especially important because of the recent poster presentation of the breast formula at AACR (American Association for Cancer Research), demonstrating its dramatic ability to decrease breast to lung metastasis in an orthotopic triple negative breast cancer animal model.

In addition to examining the aggressive behavior of breast and prostate cancer cells, researchers also assessed levels of urokinase plasminogen activator (uPA), a protein secreted by cancer cells. High levels of uPA promote cell adhesion, migration and invasion, contributing to cancer
metastasis. As a result, uPA is used as a bio-marker for invasive cancer cells. Previous studies had shown that the poly-botanicals alone suppressed uPA expression. The current study shows that uPA secretion and cancer cell migration were further restricted when cancer cells were
treated with the breast or prostate formulas combined with MCP.

For more information on the following:
*           Breast Health Formula www.BreastHealthSolutions.org
*           Prostate Health Formula www.ProstateHealthSolutions.org
*           Modified Citrus Pectin www.MCPRecommends.org
*           Published Study http://tinyurl.com/cpukkhq

Source: Jiang J, Eliaz I, Sliva D. Synergistic and Additive Effects of Modified Citrus Pectin With Two Polybotanical Compounds, in the Suppression of Invasive Behavior of Human Breast and Prostate Cancer Cells. Integr Cancer Ther. 2012 Apr 24. doi: 10.1177/1534735412442369

About Better Health Publishing

Better Health Publishing (BHP) focuses on the publication of key works promoting health and wellness. BHP believes that education and accessible information are the core components of a healthy and sustainable society.

This news release was issued on behalf of Newswise™. For more information, visit http://www.newswise.com.

SOURCE Better Health Publishing



Featured Video

Journalists and Bloggers

Visit PR Newswire for Journalists for releases, photos, ProfNet experts, and customized feeds just for Media.

View and download archived video content distributed by MultiVu on The Digital Center.

Share with Twitter Share with LinkedIn
 

Custom Packages

Browse our custom packages or build your own to meet your unique communications needs.

Start today.

 

 
 

PR Newswire Membership

Fill out a PR Newswire membership form or contact us at (888) 776-0942.

 
 

Learn about PR Newswire services

Request more information about PR Newswire products and services or call us at (888) 776-0942.

 

Online Member Center

Not a Member?
Click Here to Join
Login
Search News Releases
Advanced Search
Search
  1. PR Newswire Services
  2. Knowledge Center
  3. Browse News Releases
  4. Contact PR Newswire
  5. Send a News Release