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Displaying Results 7276-7300 of 12283 "'L'"

Nov 07, 2025, 01:00 ET Harbour BioMed and Evinova China Announce Strategic AI Collaboration to Accelerate AI-Enabled Drug Development

antibody technology platform, Harbour Mice®, generates fully human monoclonal antibodies in both the conventional two heavy and two light chain (H2L2) format and the heavy chain-only (HCAb) format. Building upon HCAb antibodies, the HCAb-based immune cell engagers (HBICE®) bispecific antibody

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Nov 06, 2025, 21:22 ET 世界初の APOC3 を標的とした高脂血症向け遺伝子編集治療薬

ける両アレル突然変異によって引き起こされる稀な常染色体劣性疾患であり、空腹時トリグリセリド(TG)が10 mmol/L(885 mg/dL)以上、世界的な有病率は10万人に1人〜100万人に1人とされています。MCSは、遺伝的要因、生活習慣、または代謝性疾患の複雑な相互作用によって発症し、世界的な有病率は最大で600人に1人とされています。 現在のカイロミクロン血症の治療は主に、急性膵炎のリスク閾値(<5.7 mmol/L または 500 mg/dL)未満に空腹時トリグリセリド(TG)値を管理することを目的としています。しかし、既存のトリグリセリド低下薬では十分な効果が得られないことが多く、また超低脂肪食は長期的な継続が困難です。

More news about: CorrectSequence Therapeutics


Nov 06, 2025, 20:30 ET La Fundación Michael J. Fox para la Investigación sobre Parkinson celebra a los votantes de Texas por la aprobación de la Proposición 14 que asegura $3 mil millones para la investigación de enfermedades cerebrales

seres queridos que también enfrentan esta enfermedad, he visto lo poderoso que es cuando nuestra comunidad se une para impulsar el cambio", señaló María L. De León, doctora en medicina, residente del este de Texas, especialista en trastornos del movimiento y miembro del Consejo de Pacientes de la MJFF. "La

More news about: The Michael J. Fox Foundation for Parkinson's Research


Nov 06, 2025, 20:00 ET 復星國際榮獲《財資》雜誌頒發的「2025年財資企業永續領導獎金獎」及「最佳可持續發展團隊獎」

全球首個獲批用於一線治療小細胞肺癌的抗PD-1單抗。截至目前,H藥已在中國、歐盟、英國、新加坡、印度等近40個國家和地區獲批上市,惠及全球逾11萬名患者。 今年以來,復星在創新藥領域實現多點破局。HLX43是一款靶向PD-L1的抗體偶聯藥物(ADC),正在中、美、日、澳等國家開展非小細胞肺癌、胸腺癌等實體瘤的臨床研究。目前,全球範圍內尚無PD-L1 ADC獲批上市,HLX43有潛力成為高效、安全的「廣譜抗癌藥」。此外,在小分子創新藥方面,復星自研的靶向藥物復邁寧獲批兩項罕見病適應症,填補了相關罕見病腫瘤領域的治療空白。

More news about: 復星


Nov 06, 2025, 20:00 ET Fosun International Honored with Gold Award and Best Sustainability Team at The Asset Corporate Sustainability Leadership Awards 2025

of innovative drugs. HLX43, a PD-L1-targeting antibody-drug conjugate (ADC) is undergoing clinical studies for solid tumors such as non-small cell lung cancer and thymic carcinoma in countries including China, the United States, Japan, and Australia. Currently, no PD-L1 ADC has been approved globally,

More news about: Fosun


Nov 06, 2025, 19:10 ET ACAAI 2025 | CS2015 (OX40L/TSLP Bispecific Antibody) Makes International Debut

CS2015 lead molecule demonstrated potent inhibition of OX40L/OX40 and TSLP/TSLPR downstream signaling: CS2015 potently interrupted the engagement of hOX40L on hOX40 reporter cells and hTSLP on hTSLPR/IL-7Rα reporter cells, respectively;

More news about: CStone Pharmaceuticals


Nov 06, 2025, 19:00 ET 里程碑突破!全球首個APOC3基因編輯臨床治療高血脂獲得成功

Syndrome,MCS)。其中FCS是一種罕見的常染色體隱性遺傳病,由於脂蛋白脂肪酶(Lipoprotein lipase,LPL)基因或參與調控LPL活性的關鍵基因發生雙等位基因突變,導致脂蛋白脂肪酶功能受損,使甘油三脂的分解代謝產生障礙,從而造成體內乳糜微粒的蓄積,通常患者的空腹TG水準≥10 mmol/L (885 mg/dL),全球發病率在十萬分之一到百萬分之一之間;而MCS則由多種因素引起的病理狀態,其發病受遺傳背景、生活習慣或其他代謝疾病共同影響,全球發病率高達1/600。 目前,高乳糜微粒血症的主要治療策略是將患者的空腹甘油三脂(TG)水準控制在急性胰腺炎風險閾值以下(通常需<5.7

More news about: CorrectSequence Therapeutics


Nov 06, 2025, 18:52 ET Lunai Bioworks 在臨床前人源化模型內,實現原發性和轉移性胰臟腫瘤的完全消退,標誌為同種異體癌症免疫療法的突破

的療法利用基因工程改造的樹突狀細胞(幹細胞創造的特殊免疫細胞),這些細胞經過基因增強而啟動人體免疫系統來抗癌。該刊登詳細介紹該平台的第二代臨床合規版本,並提供推進該療法持續合作對話的關鍵證據。 這項新發表建基於 Lunai 的較早研究(Vaccines 2025 Jul 12;13(7):749; doi:10.3390/vaccines13070749),該研究首次在人源化胰腺癌小鼠體內證明,經過基因改造過度表達 CD40L、CD93 和 CXCL13 的 CD34+ 造血幹細胞 (HSC) 衍生的樹突狀細胞 (DC) 具備強大抗腫瘤活性。雖然最初研究採用研究級慢病毒載體,但最新報告描述一種最佳化兼符合臨床規範的構建體。該構建體保持同等療效,同時改進設計與製造特性,從而支持未來臨床轉化。

More news about: Lunai Bioworks Inc.


Nov 06, 2025, 18:00 ET Aily Labs Raises $80 Million to Scale AI that Drives Performance across Fortune 500 Companies

extract real business value from it. That's what compelled us to invest in Aily Labs – their platform delivers actionable insights that drive measurable P&L impact," said Pegah Ebrahimi, Co-founder & Managing Partner at FPV Ventures. "CEOs tell us they're making different decisions because of

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Nov 06, 2025, 18:00 ET Aily Labs Raises $80 Million to Scale AI that Drives Performance across Fortune 500 Companies

extract real business value from it. That's what compelled us to invest in Aily Labs – their platform delivers actionable insights that drive measurable P&L impact," said Pegah Ebrahimi, Co-founder & Managing Partner at FPV Ventures. "CEOs tell us they're making different decisions because of

More news about: Aily Labs


Nov 06, 2025, 18:00 ET ATD Saudi Arabia 2025: Shaping the Future-Ready Workforce for Vision 2030

transformation into lasting growth." Since its inception, ATD Saudi Arabia Conference has evolved into a cornerstone of the Kingdom's L&D landscape, serving as a catalyst for change and a bridge between global best practices and regional innovation. Over the years, it has hosted some

More news about: Association for Talent Development (ATD)


Nov 06, 2025, 16:15 ET MAIN STREET ANNOUNCES THIRD QUARTER 2025 RESULTS

"August 2028 Notes") In commenting on the Company's operating results for the third quarter of 2025, Dwayne L. Hyzak, Main Street's Chief Executive Officer, stated, "We are pleased with our performance in the third quarter, which resulted in another quarter of

More news about: Main Street Capital Corporation


Nov 06, 2025, 16:05 ET FLOWERS FOODS, INC. REPORTS THIRD QUARTER 2025 RESULTS

partially offset, inflationary pressure or tariffs (including retaliatory tariffs) on the cost of our products, including ingredient and packaging costs; (l) disruptions in our direct-store-delivery distribution model, including litigation or an adverse ruling by a court or regulatory or governmental body

More news about: Flowers Foods, Inc.


Nov 06, 2025, 15:56 ET ALERT: Rowley Law PLLC is Investigating Proposed Acquisition of Golden Entertainment, Inc.

securities law violations by Golden Entertainment, Inc. (NASDAQ: GDEN) and its board of directors concerning the proposed acquisition of the company by Blake L. Sartini and VICI Properties Inc. (NYSE: VICI). Stockholders will receive $2.75 in cash and 0.902 shares of VICI Properties common stock for each share

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Nov 06, 2025, 15:46 ET Halper Sadeh LLC Encourages BHF, GDEN, FRGE Shareholders to Contact the Firm to Discuss Their Rights

Golden Entertainment, Inc.'s (NASDAQ: GDEN)'s sale of its operating assets to Blake L. Sartini and affiliates, and seven of its casino real estate assets to VICI Properties Inc. Under the terms of the proposed transaction,

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Nov 06, 2025, 15:20 ET Monroe University's Mustangs Athletic Program Joins Central Atlantic Collegiate Conference

energy, talent, and commitment Monroe's student-athletes will bring as we continue to elevate the experience for all teams in our conference," said John L. Hopkins, Chair of the CACC Presidents Council and President and CEO of Post University. "I join my fellow administrators throughout

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Nov 06, 2025, 14:59 ET Toyota impulsa las posibilidades en SEMA 2025

Renace un ícono: el Turbo Trail Cruiser combina el clásico Land Cruiser FJ60 de 1985 con la potencia moderna del i-FORCE 3.4L con motor biturbo V6 de Toyota. El resultado es un auto restaurado y modernizado que mantiene au apariencia original de fábrica pero que ofrece un rendimiento

More news about: Toyota Motor North America


Nov 06, 2025, 14:50 ET Perché il robot tagliaerba Raccoon 2 SE è così conveniente: RoboUP rende la vita smart accessibile a tutti

puoi premere un pulsante e andartene, senza dover fare altro - una vera esperienza plug and play. Il Raccoon 2 SE verrà lanciato l'11 novembre 2025: restano solo 7 giorni per i primi sostenitori! Prenota subito il tuo posto Super Early Bird con un

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Nov 06, 2025, 14:08 ET Global Health Leaders Unveil Roadmap for Healthcare Transformation at Future of Health (FOH) Summit

"We need to think and act globally to address the many common challenges we face and to spur innovation across borders," said Dr. Peter L. Slavin, President and CEO of Cedars-Sinai. "Cedars-Sinai is proud to play our part in fostering this international dialogue to improve the quality

More news about: Future of Health Inc (FOH)


Nov 06, 2025, 13:53 ET SPLICE Software and Solvrays Partner to Transform P&C and L&A Workflows Through Intelligent Communications and Agentic Automation

omnichannel communications platform and Solvrays' agentic automation engine, enabling Property & Casualty (P&C) and Life & Annuities (L&A) carriers to move from communication to coordinated action seamlessly. "Combining SPLICE's  AI voice, and text with Solvrays'

More news about: SPLICE Software Inc


Nov 06, 2025, 12:50 ET NIIT Learning Systems Limited (NIIT MTS) Announces Q2 FY 2026 (July-September 2025) Results

training sector of the corporate learning and development (L&D) market.  About NIIT Learning Systems Limited (NIIT MTS) NIIT MTS is the trusted and award-winning L&D and talent partner for the world's leading companies

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Nov 06, 2025, 12:21 ET Shareholder Alert: The Ademi Firm investigates whether Golden Entertainment Inc. is obtaining a Fair Price for its Public Shareholders

investigating Golden (NASDAQ: GDEN) for possible breaches of fiduciary duty and other violations of law in its recently announced transaction with Blake L. Sartini and affiliates.

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Nov 06, 2025, 11:05 ET 再鼎醫藥公布 2025年第三季度財務業績和近期公司進展

Meeting(AACR-NCI-EORTC)上公布的zocilurtatug pelitecan (zoci, DLL3 ADC)(前稱ZL-1310)的數據,持續展現出同類首創與同類最佳潛力,為近期啟動的用於治療2L+廣泛期小細胞肺癌(ES-SCLC)的全球注冊性研究提供了有力支持 – 推進其他高潛力全球項目,包括啟動ZL-1503

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Nov 06, 2025, 10:53 ET Life Time Expands CTR Reformer Workout Nationwide Amid Soaring Demand

lives through its more than 185 athletic country clubs across the U.S. and Canada, the complimentary and comprehensive Life Time app featuring its L•AI•C™ AI-powered health companion, and more than 30 iconic athletic events. Serving people ages 90 days to 90+ years, the Life Time ecosystem uniquely delivers

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Nov 06, 2025, 10:11 ET Center for Heirs' Property Marks 20 Years with Expansion to East Texas, Helping More Families Secure Their Land and Legacy

most—the roof over their heads and the land under their feet. This has allowed CHP to deepen its impact in critical areas of the country," said Dr. Jennie L. Stephens, CEO of the Center for Heirs' Property. "East Texas families, much like those in Appalachia, have deep ties to their

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